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Scientists Decipher Genome of Bacterium that Helps Clean Up Major Groundwater Pollutants
Cryptococcus Study Sheds Light On How Fungi Cause Disease
Genome Comparison of Four Campylobacter Strains Yields New Genetic Markers and Clues to Virulence
In a study that could benefit medical and food-safety research, scientists have used the tools of comparative genomics to find new clues about why some strains of the bacterium Campylobacter - which each year cause more than 400 million cases of gastrointestinal disease - are more virulent than others. The analysis is helping researchers develop more comprehensive detection methods for analyzing human and environmental isolates of the bacteria.
Microbe's Genome Reveals Insights Into Ocean Ecology
Unexpected findings about the genetic makeup of a marine microbe have given scientists a new perspective on how bacteria make a living in the ocean - a view that may prove useful in wider studies of marine ecology. The analysis by TIGR and collaborators of the DNA sequence of Silicibacter pomeroyi found that the metabolic strategies of marine bacterioplankton are more diverse and less conventional than previously thought.
Innovative Metagenomics Strategy Used To Study Oral Microbes
In an innovative new project, TIGR scientists and collaborators are using a metagenomics strategy to explore the complex mix of microbes in the human mouth. The research could help improve the diagnosis and treatment of periodontitis and other oral diseases.
Influenza Genome Sequencing Project Is Launched
TIGR will sequence a large number of human isolates of the influenza virus as part of a landmark influenza genome sequencing project announced Monday by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. The project aims to help scientists better understand how flu viruses evolve as they spread through the population.
TIGR and Virginia Tech Sign Memorandum for New Alliance
A new alliance between TIGR and Virginia Tech University is expected to enhance the Institute's computational and experimental capacity as well as enrich the university's basic research in the life sciences. The Memorandum of Understanding, announced Monday, anticipates joint research projects, shared use of related facilities, adjunct faculty appointments, and opportunities for students to participate in research.
TIGR's Fraser, Salzberg Honored As AAAS Fellows
TIGR President Claire M. Fraser and Senior Bioinformatics Director Steven L. Salzberg have been named as Fellows of the American Association for the Advancement of Science (AAAS) in recognition of their contributions to genomics and bioinformatics.
Computational Genomics Conference To Attract Leading Scientists
Comparative genomics, sequence assembly, gene expression analysis and genome annotation are among the hot topics to be discussed at the 7th annual Conference on Computational Genomics, which will be held October 21-24 in Reston, VA. The meeting is jointly sponsored by TIGR and The Jackson Laboratory.
J. Craig Venter Announces Consolidation of Three Research Organizations Into One New Not-For-Profit Organization — The J. Craig Venter Institute
The Center for Advancement of Genomics (TCAG), Institute for Biological Energy Alternatives (IBEA), and J. Craig Venter Science Foundation Joint Technology Center (JTC) consolidated to form J. Craig Venter Institute
Scientists Decipher Genome of Biothreat Pathogen
Highly Regulated Virulence Genes and Genomic Instability Found in the Infectious Horse Pathogen Burkholderia mallei
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Digging out from the storm
The next day offered more snow and wind: we still needed handheld radios anytime we ventured between the warming hut and any of the vehicles. The wind was so strong that snow began drifting up through the dive hole in the warming hut, and the windows completely glazed over with snow. At one...
Out onto the ice
It took an enormous amount of effort, but on Thursday we ventured out onto the sea ice with our train of sleds and snow machines. The tucker is our strongest (and slowest) vehicle, and it is pulling both our yellow research sled and a pair of snowmobiles. The red Pisten-Bully is pulling a...
Around Mac-town
We are now fully packed and our mobile research sled is ready to go. We are waiting for some final repairs on the Pisten-Bully which will pull our supply sled. The mobile laboratory sled will be pulled by the Sno-Cat Tucker, which also has cab space for six (riding in the mobile lab would...
Ice diatoms!
Today has been a day of preparations, as tomorrow we hope to leave McMurdo Station and head out on the sea ice. Our mobile sled is almost ready for deployment: the carpenters who work for the US Antarctic Program are quite amazing, and our sled has filtration racks for separating different...
Sea-ice class
Today Abigail Noble and I took a Hagglund transporter out onto the Ross Sea to learn the basics of sea ice safety and ice dynamics. The sea ice on McMurdo Sound can be 2 meters thick, but this ice is constantly changing, and when you drive along its surface, you can't assume that it is...
Happy Camp
Our project on the Ross Sea will take us far from heated facilities of McMurdo Station, so all members of our team need to attend "Happy Camp", a two day course on snow camping and basic Antarctic survival. Happy Camp is held out on the McMurdo Ice Shelf, and it is an immersion program in...
McMurdo Station
Entering McMurdo is like entering a modern mining town: lots of exposed rock and unpaved streets, above ground utilities and bare-bones architecture. Utilitarian. From the airport we were taken to a briefing room, introduced to our science coordinators, and given our shcedules. Since I am...
Transport to the ice
Wednesday morning started with a 5AM taxi ride to the US Antarctic Program's processing center at the Christchurch airport, where we had to repack our bags and put on our emergency cold weather gear for the flight. Our plane was the C-17 Globemaster III, a large military transport plane more...
Polynya opens in the Ross Sea
A helicopter pilot recently sent us an image of the area we are planning to sample, and the stable sea ice we intended to use as a platform for drilling and sampling is now a giant stretch of open seawater! A large opening like this is a polynya, a term borrowed from the Russian...
Christchurch, New Zealand
Greetings from Christchurch, New Zealand, the anteroom to Antarctica. My colleagues and I have been here for several days now, running last minute errands, getting equipped with cold weather gear, and waiting for a flight south to McMurdo Station. The flight here was remarkable only in it's...
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Can CRISPR help stop African Swine Fever?
Gene editing could create a successful vaccine to protect against the viral disease that has killed close to 2 million pigs globally since 2021.
Getting Under the Skin
Amid an insulin crisis, one project aims to engineer microscopic insulin pumps out of a skin bacterium.
Planet Microbe
There are more organisms in the sea, a vital producer of oxygen on Earth, than planets and stars in the universe.
The Next Climate Change Calamity?: We’re Ruining the Microbiome, According to Human-Genome-Pioneer Craig Venter
In a new book (coauthored with Venter), a Vanity Fair contributor presents the oceanic evidence that human activity is altering the fabric of life on a microscopic scale.
Lessons from the Minimal Cell
“Despite reducing the sequence space of possible trajectories, we conclude that streamlining does not constrain fitness evolution and diversification of populations over time. Genome minimization may even create opportunities for evolutionary exploitation of essential genes, which are commonly observed to evolve more slowly.”
Even Synthetic Life Forms With a Tiny Genome Can Evolve
By watching “minimal” cells regain the fitness they lost, researchers are testing whether a genome can be too simple to evolve.
Privacy concerns sparked by human DNA accidentally collected in studies of other species
Two research teams warn that human genomic “bycatch” can reveal private information
Scientists Unveil a More Diverse Human Genome
The “pangenome,” which collated genetic sequences from 47 people of diverse ethnic backgrounds, could greatly expand the reach of personalized medicine.
First human ‘pangenome’ aims to catalogue genetic diversity
Researchers release draft results from an ongoing effort to capture the entirety of human genetic variation.
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