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Scientists Decipher Genome of Bacterium that Helps Clean Up Major Groundwater Pollutants
Cryptococcus Study Sheds Light On How Fungi Cause Disease
Genome Comparison of Four Campylobacter Strains Yields New Genetic Markers and Clues to Virulence
In a study that could benefit medical and food-safety research, scientists have used the tools of comparative genomics to find new clues about why some strains of the bacterium Campylobacter - which each year cause more than 400 million cases of gastrointestinal disease - are more virulent than others. The analysis is helping researchers develop more comprehensive detection methods for analyzing human and environmental isolates of the bacteria.
Microbe's Genome Reveals Insights Into Ocean Ecology
Unexpected findings about the genetic makeup of a marine microbe have given scientists a new perspective on how bacteria make a living in the ocean - a view that may prove useful in wider studies of marine ecology. The analysis by TIGR and collaborators of the DNA sequence of Silicibacter pomeroyi found that the metabolic strategies of marine bacterioplankton are more diverse and less conventional than previously thought.
Innovative Metagenomics Strategy Used To Study Oral Microbes
In an innovative new project, TIGR scientists and collaborators are using a metagenomics strategy to explore the complex mix of microbes in the human mouth. The research could help improve the diagnosis and treatment of periodontitis and other oral diseases.
Influenza Genome Sequencing Project Is Launched
TIGR will sequence a large number of human isolates of the influenza virus as part of a landmark influenza genome sequencing project announced Monday by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. The project aims to help scientists better understand how flu viruses evolve as they spread through the population.
TIGR and Virginia Tech Sign Memorandum for New Alliance
A new alliance between TIGR and Virginia Tech University is expected to enhance the Institute's computational and experimental capacity as well as enrich the university's basic research in the life sciences. The Memorandum of Understanding, announced Monday, anticipates joint research projects, shared use of related facilities, adjunct faculty appointments, and opportunities for students to participate in research.
TIGR's Fraser, Salzberg Honored As AAAS Fellows
TIGR President Claire M. Fraser and Senior Bioinformatics Director Steven L. Salzberg have been named as Fellows of the American Association for the Advancement of Science (AAAS) in recognition of their contributions to genomics and bioinformatics.
Computational Genomics Conference To Attract Leading Scientists
Comparative genomics, sequence assembly, gene expression analysis and genome annotation are among the hot topics to be discussed at the 7th annual Conference on Computational Genomics, which will be held October 21-24 in Reston, VA. The meeting is jointly sponsored by TIGR and The Jackson Laboratory.
J. Craig Venter Announces Consolidation of Three Research Organizations Into One New Not-For-Profit Organization — The J. Craig Venter Institute
The Center for Advancement of Genomics (TCAG), Institute for Biological Energy Alternatives (IBEA), and J. Craig Venter Science Foundation Joint Technology Center (JTC) consolidated to form J. Craig Venter Institute
Scientists Decipher Genome of Biothreat Pathogen
Highly Regulated Virulence Genes and Genomic Instability Found in the Infectious Horse Pathogen Burkholderia mallei
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In the News
We docked in the Volvo Ocean Race Village for a week. It was very exciting to be so close to all of the activities surrounding the race. Over the week Dr. Venter and Karolina and I were interviewed by many local and national TV, radio stations and newspapers. Here are some links to a few of the...
The Volvo Ocean Race
We arrived in Sandhamn at 10 p.m. on June 15th. It was perfect timing because the Volvo Ocean Race boats were arriving around 11 p.m. The Volvo Ocean Race, formally known as the Whitbread “Around the World Race,” began in Alicante on October 11th 2008 and ends in St. Petersburg on June 25th...
Heading to the Mother Land — Sweden
After transiting through the Kiel Canal, the waterway that links the North Sea to the Baltic Sea, and welcoming Dr. Venter in a rainy Copenhagen, we embarked for Sweden, my home and one of the main destinations of our 2009 expedition. It was a proud and special moment for me when first mate,...
Sampling in Helgoland — A warm German welcome for the Sorcerer II
After a little more than two weeks in Plymouth, UK the Sorcerer II set sail on June 3rd. We were sad to say goodbye to our new friends at PLM, but we were grateful for their hospitality, friendship and scientific collaboration. We're looking forward to coming back through Plymouth in the fall....
Cornish Pasties and Jellyfish at the MBA
On Monday we were invited to the Marine Biology Association (MBA) and the Sir Alister Hardy Foundation for Ocean Science (SAHFOS) for lunch and a more extensive tour of the laboratories and SAHFOS. This was an excellent opportunity for crew members who missed the first tour. A beautiful table...
The Final Plymouth Sample
On Thursday, May 28th the Sorcerer II crew, accompanied by Dr. Jack Gilbert and two of his PhD students, headed out for one final sampling trip. The destination was E-1, a long term research station for PML located about 25 miles off the coast of Plymouth in the English Channel. As we...
First Sampling in Plymouth Reveals Interesting Blooms — BBC Cameras capture it all!
After a couple of days in Plymouth we were ready for the first of two intense sampling days together with the Plymouth Marine Laboratory (PML). We had heard rumours about blooms of Phaeocystis, a conspicuous bloom-former in the North Sea and English Channel. When it blooms, it turns the...
Days of Discovery: Plymouth, Sea Urchin Cell Division and More Plankton
After a few days of fairly rough weather and winds up to 50 knots we finally spotted land and made our way to Plymouth. With our social interactions having been restricted to a pod of pilot whales and a few tankers passing through the night, we were excited to see a welcoming committee,...
England, Here We Come!
In calm and clear conditions on May 11 Sorcerer II set sail for Plymouth, England. We enjoyed our brief stay in the Azores, but we were all excited to get to the U.K. and complete our North Atlantic crossing. As I mentioned in previous entries, we took samples near areas studied by...
Land Horta! The Sorcerer II on Faial Island, the Azores
We sailed into Horta on the island of Failal Saturday, May 9th around 1pm. The Sorcerer II crew was excited to visit the island but then again, we were just happy to walk on land and sleep in a bed that was not rolling from side to side! As usual when we arrive in a new port, we cleared...
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Can CRISPR help stop African Swine Fever?
Gene editing could create a successful vaccine to protect against the viral disease that has killed close to 2 million pigs globally since 2021.
Getting Under the Skin
Amid an insulin crisis, one project aims to engineer microscopic insulin pumps out of a skin bacterium.
Planet Microbe
There are more organisms in the sea, a vital producer of oxygen on Earth, than planets and stars in the universe.
The Next Climate Change Calamity?: We’re Ruining the Microbiome, According to Human-Genome-Pioneer Craig Venter
In a new book (coauthored with Venter), a Vanity Fair contributor presents the oceanic evidence that human activity is altering the fabric of life on a microscopic scale.
Lessons from the Minimal Cell
“Despite reducing the sequence space of possible trajectories, we conclude that streamlining does not constrain fitness evolution and diversification of populations over time. Genome minimization may even create opportunities for evolutionary exploitation of essential genes, which are commonly observed to evolve more slowly.”
Even Synthetic Life Forms With a Tiny Genome Can Evolve
By watching “minimal” cells regain the fitness they lost, researchers are testing whether a genome can be too simple to evolve.
Privacy concerns sparked by human DNA accidentally collected in studies of other species
Two research teams warn that human genomic “bycatch” can reveal private information
Scientists Unveil a More Diverse Human Genome
The “pangenome,” which collated genetic sequences from 47 people of diverse ethnic backgrounds, could greatly expand the reach of personalized medicine.
First human ‘pangenome’ aims to catalogue genetic diversity
Researchers release draft results from an ongoing effort to capture the entirety of human genetic variation.
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