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Scientists Decipher Genome of a Fungus That Causes Life-Threatening Infections in Persons With Impaired Immunity
Cryptococcus Study Sheds Light On How Fungi Cause Disease
Scientists Reveal Molecular Secrets of the Malaria Parasite
Groundbreaking Research Project May Help Boost Vaccine Development
Scientists Decipher Genome of Bacterium that Helps Clean Up Major Groundwater Pollutants
Cryptococcus Study Sheds Light On How Fungi Cause Disease
Genome Comparison of Four Campylobacter Strains Yields New Genetic Markers and Clues to Virulence
In a study that could benefit medical and food-safety research, scientists have used the tools of comparative genomics to find new clues about why some strains of the bacterium Campylobacter - which each year cause more than 400 million cases of gastrointestinal disease - are more virulent than others. The analysis is helping researchers develop more comprehensive detection methods for analyzing human and environmental isolates of the bacteria.
Microbe's Genome Reveals Insights Into Ocean Ecology
Unexpected findings about the genetic makeup of a marine microbe have given scientists a new perspective on how bacteria make a living in the ocean - a view that may prove useful in wider studies of marine ecology. The analysis by TIGR and collaborators of the DNA sequence of Silicibacter pomeroyi found that the metabolic strategies of marine bacterioplankton are more diverse and less conventional than previously thought.
Innovative Metagenomics Strategy Used To Study Oral Microbes
In an innovative new project, TIGR scientists and collaborators are using a metagenomics strategy to explore the complex mix of microbes in the human mouth. The research could help improve the diagnosis and treatment of periodontitis and other oral diseases.
Influenza Genome Sequencing Project Is Launched
TIGR will sequence a large number of human isolates of the influenza virus as part of a landmark influenza genome sequencing project announced Monday by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. The project aims to help scientists better understand how flu viruses evolve as they spread through the population.
TIGR and Virginia Tech Sign Memorandum for New Alliance
A new alliance between TIGR and Virginia Tech University is expected to enhance the Institute's computational and experimental capacity as well as enrich the university's basic research in the life sciences. The Memorandum of Understanding, announced Monday, anticipates joint research projects, shared use of related facilities, adjunct faculty appointments, and opportunities for students to participate in research.
TIGR's Fraser, Salzberg Honored As AAAS Fellows
TIGR President Claire M. Fraser and Senior Bioinformatics Director Steven L. Salzberg have been named as Fellows of the American Association for the Advancement of Science (AAAS) in recognition of their contributions to genomics and bioinformatics.
Computational Genomics Conference To Attract Leading Scientists
Comparative genomics, sequence assembly, gene expression analysis and genome annotation are among the hot topics to be discussed at the 7th annual Conference on Computational Genomics, which will be held October 21-24 in Reston, VA. The meeting is jointly sponsored by TIGR and The Jackson Laboratory.
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Science Festivals
With spring around the corner (or at least we hope), there are several upcoming science festivals. These festivals are designed to provide students and families opportunities to find out what is happening in local science research institutes, universities and companies. These organizations...
Waste-to-Electricity?
Many of us don’t spend a lot of time pondering wastewater treatment unless we absolutely have to. However, we may need to start rethinking this dirty job. In the United States wastewater treatment is a multi-billion dollar industry that is facing major challenges in the...
300 Papers
Congratulations to Ken Nealson for publishing his 300th paper! Ken has been a driving force in microbiology for 40 years having published several seminal papers in microbial ecology. In the 1980s he helped to pioneer the field of geobiology and discovered bacteria that thrive on metal. Dr....
2010 Internship Program Ready to Go
Are you thinking about summer already? We are!! The 2010 Summer Internship Program is open to accept applications. Last year, we received and reviewed over 300 applications from all over the US and the world for our summer program. Interns were selected to work in most of the research groups...
Scientist Spotlight: Karen Nelson
Karen’s interest in the natural world was sparked at a young age. Born in Jamaica, she enjoyed the outdoors and wonders of nature. Karen was drawn to animals and wanted to become a veterinarian, but after taking some human and animal nutrition courses in college she was hooked on...
Antarctic Epiblog: Leaving McMurdo
Ice formation outside McMurdo Station After we took our samples out at the ice edge, we returned to McMurdo Station for several intense days of demobilization. We had to return all of the large drills, power equipment and camping gear, and spent a considerable time preparing our...
Station IV: The Ice Edge
Our last station in our Ross Sea transect was out at the ice edge, about two miles north of our previous station, Station III. We were interested to see how plankton in the open polynya were different from the phytoplankton we isolated from areas locked in sea-ice. Polynyas are ice-free areas...
Station III: approaching the ice edge
As we were finishing up our work at Station II, we called MacOps, the radio command center for McMurdo Station, and got a 24 hour weather update: a high to the north of Ross Island was blocking a storm in the south, and we were caught in the middle. The prediction: snow, and lots of it. We had...
Station II, Inaccessible Island
The second storm of our trip hit us while we were packing up Station I for a return to McMurdo. The winds began gusting over 50 miles per hour, and the visibility dropped to near zero. We had already packed up camp, but the orders came in over the radio that Condition 1 had been imposed on the...
Kudos to Ken!
JCVI Professor, Kenneth Nealson, has been selected by the American Society of Microbiology to receive an award that recognizes distinguished accomplishments in interdisciplinary research and training in microbiology. The 2010 David C. White Research and Mentoring Award will be awarded to Ken...
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Can CRISPR help stop African Swine Fever?
Gene editing could create a successful vaccine to protect against the viral disease that has killed close to 2 million pigs globally since 2021.
Getting Under the Skin
Amid an insulin crisis, one project aims to engineer microscopic insulin pumps out of a skin bacterium.
Planet Microbe
There are more organisms in the sea, a vital producer of oxygen on Earth, than planets and stars in the universe.
The Next Climate Change Calamity?: We’re Ruining the Microbiome, According to Human-Genome-Pioneer Craig Venter
In a new book (coauthored with Venter), a Vanity Fair contributor presents the oceanic evidence that human activity is altering the fabric of life on a microscopic scale.
Lessons from the Minimal Cell
“Despite reducing the sequence space of possible trajectories, we conclude that streamlining does not constrain fitness evolution and diversification of populations over time. Genome minimization may even create opportunities for evolutionary exploitation of essential genes, which are commonly observed to evolve more slowly.”
Even Synthetic Life Forms With a Tiny Genome Can Evolve
By watching “minimal” cells regain the fitness they lost, researchers are testing whether a genome can be too simple to evolve.
Privacy concerns sparked by human DNA accidentally collected in studies of other species
Two research teams warn that human genomic “bycatch” can reveal private information
Scientists Unveil a More Diverse Human Genome
The “pangenome,” which collated genetic sequences from 47 people of diverse ethnic backgrounds, could greatly expand the reach of personalized medicine.
First human ‘pangenome’ aims to catalogue genetic diversity
Researchers release draft results from an ongoing effort to capture the entirety of human genetic variation.
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