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Fighting Back Against Flu
The 1918 influenza pandemic, which affected 500 million people globally and caused 50-100 million deaths, was the most severe pandemic in recorded history. Over the course of the last 100 years, advances in science and medicine have provided the tools to address influenza much more successfully. However, despite vaccines and supportive medical interventions such as antivirals and antibiotics, influenza remains a public health problem and can be deadly for the very young, the elderly, and...
Rapid cDNA sequencing (expressed sequence tags) from a directionally cloned human infant brain cDNA library.
A human infant brain cDNA library, made specifically for production of expressed sequence tags (ESTs) was evaluated by partial sequencing of over 1,600 clones. Advantages of this library, constructed for EST sequencing, include the use of directional cloning, size selection, very low numbers of mitochondrial and ribosomal transcripts, short polyA tails, few non-recombinants and a broad representation of transcripts. 37% of the clones were identified, based on matches to over 320 different...
JCVI Scientist Tackles Global Sanitation Challenges
Orianna Bretschger received her B.S. in Physics and Astronomy at the University of Northern Arizona. After a five- year career in aerospace and consulting, she completed a PhD in Materials Science at the University of Southern California. Eager to focus her efforts on alternative energy and sustainability, she joined the J. Craig Venter Institute in 2008. Over the course of her research tenure, Dr. Bretschger has established a productive team of researchers dedicated to understanding...
About Lucy Stewart
Lucy Stewart, MBA, serves as the director of project and operational management at J. Craig Venter Institute, boasting nearly two decades of unwavering dedication to pioneering research project management. Her career is characterized by a diverse and impactful portfolio of projects that are centered on intricate, longitudinal, infectious disease and bioinformatics projects, solidifying her as a distinguished professional in the field. Beyond her role in project oversight, Ms.
2019 Summer Internship Program
The 2019 Summer Internship Program which wrapped up in August was another rousing success at the J. Craig Venter Institute. Faculty and staff in both the Rockville (MD) and La Jolla (CA) campuses mentored and trained 25 students (high school, undergraduate, and graduate students) from across the country in cutting-edge technologies related to the biomedical field. High school students participated in the internship for 8-weeks and undergraduate and graduate students took...
Assessing diversity and biogeography of aerobic anoxygenic phototrophic bacteria in surface waters of the Atlantic and Pacific Oceans using the Global Ocean Sampling expedition metagenomes.
Aerobic anoxygenic photosynthetic bacteria (AAnP) were recently proposed to be significant contributors to global oceanic carbon and energy cycles. However, AAnP abundance, spatial distribution, diversity and potential ecological importance remain poorly understood. Here we present metagenomic data from the Global Ocean Sampling expedition indicating that AAnP diversity and abundance vary in different oceanic regions. Furthermore, we show for the first time that the composition of AAnP...
The HuRef Browser: a web resource for individual human genomics.
The HuRef Genome Browser is a web application for the navigation and analysis of the previously published genome of a human individual, termed HuRef. The browser provides a comparative view between the NCBI human reference sequence and the HuRef assembly, and it enables the navigation of the HuRef genome in the context of HuRef, NCBI and Ensembl annotations. Single nucleotide polymorphisms, indels, inversions, structural and copy-number variations are shown in the context of existing...
JCVI Rockville Directions
J. Craig Venter Institute 9605 Medical Center Drive, Suite 150 Rockville, MD 20850 Phone: 301-795-7000 Driving Directions From Baltimore, MD and BWI Airport Take I-95 South to I-495 West (Silver Spring). Follow I-495 West nine miles to I-270 and travel north to Shady Grove Road (Exit 8 West). Continue to the traffic light and turn left onto Shady Grove Road. Make a right at the 4th light onto Key...
The Protein Naming Utility: a rules database for protein nomenclature.
Generation of syntactically correct and unambiguous names for proteins is a challenging, yet vital task for functional annotation processes. Proteins are often named based on homology to known proteins, many of which have problematic names. To address the need to generate high-quality protein names, and capture our significant experience correcting protein names manually, we have developed the Protein Naming Utility (PNU, http://www.jcvi.org/pn-utility). The PNU is a web-based database for...
JCVI La Jolla Breaks Ground
It is official! On Tuesday, September 20th JCVI officially broke ground on a new La Jolla, California sustainable lab, to be located directly on the campus of the University of California, San Diego. Craig Venter, JCVI Founder and President along with UCSD Chancellor Marye Anne Fox; Vice Chancellor for Health Sciences and Dean of the School of Medicine, David Brenner; Director of Scripps Institution of Oceanography and Vice Chancellor for Marine Sciences, Tony Haymet; and San Diego Mayor...