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CharProtDB: a database of experimentally characterized protein annotations.
CharProtDB (http://www.jcvi.org/charprotdb/) is a curated database of biochemically characterized proteins. It provides a source of direct rather than transitive assignments of function, designed to support automated annotation pipelines. The initial data set in CharProtDB was collected through manual literature curation over the years by analysts at the J. Craig Venter Institute (JCVI) [formerly The Institute of Genomic Research (TIGR)] as part of their prokaryotic genome sequencing...
LJI Scientists Identify Potential Targets for Immune Responses to Novel Coronavirus
LA JOLLA, CA—Within two months, SARS-CoV-2, a previously unknown coronavirus, has raced around globe, infecting over a 100,000 people with numbers continuing to rise quickly. Effective countermeasures require helpful tools to monitor viral spread and understand how the immune system responds to the virus. Publishing in the March 16, 2020, online issue of Host, Cell and Microbe, a team of researchers at La Jolla Institute for Immunology, in collaboration with researchers at the J....
Chromosomal distribution of 320 genes from a brain cDNA library.
We have determined the chromosomal assignment of 320 brain expressed genes by studying the segregation of polymerase chain reaction (PCR) products in human rodent somatic cell hybrids and by genetically mapping polymorphic cDNAs using the CEPH (Centre d'Etude du Polymophisme Humaine) reference pedigrees and database. These mapped genes can function as markers on the physical map of the human genome, as well as serve as candidate disease gene loci. Distribution of these genes to the human...
About Sanjay Vashee
Sanjay Vashee is a professor in the Synthetic Biology Group and the Rockville, MD Campus Director at the J. Craig Venter Institute. After joining JCVI in 2003, Dr. Vashee helped the Synthetic Biology Group develop synthetic genomics methods and technologies that led to the creation of a synthetic organism based on Mycoplasma mycoides subspecies capri.
About Hyesun “Sunny” Jang
Hyesun “Sunny” Jang is a staff scientist at the J. Craig Venter Institute, supervised by Dr. Marcelo Freire. With a background as a veterinarian, Dr. Jang is interested in developing host-directed anti-viral strategies against diverse zoonotic viruses.
Genomics: massively parallel sequencing.
About Antony G. Peake
Antony G. Peake, CRA, serves as the Vice President of Research Administration at the J. Craig Venter Institute. Reporting to the President, Antony directs and oversees the research administration operations and management of all extramural funded research programs at the Institute.