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About Rudy L. Ruggles, Jr.
Education Harvard College, Bachelor’s Degree in Physics, plus graduate studies Harvard Business School MBA – R&D Strategy, and International Economics 1960s Senior Associate Physicist, IBM Research Lab., Condensed Matter Physics
Viral Synthetic Genomics to Engineer Large dsDNA Viruses
Viruses with large double-stranded DNA (dsDNA) genomes are a diverse group, which includes members that can infect a wide range of different hosts. Some of these viruses are important pathogens of humans and animals. Improving our ability to manipulate their genomes rapidly and accurately will increase our understanding of how these viruses replicate and cause disease and the likelihood of developing vaccines. Utilizing synthetic genomics tools developed by scientists at the J. Craig...
Sequencing and analysis of genomic fragments from the NF1 locus.
The sequence of five non-contiguous genomic fragments encompassing 14.4 kilobases from the NF1 locus have been determined by fluorescence-based automated DNA sequence analysis. These fragments included one kilobase of the NF1 coding region, which resulted in the identification of the intron/exon boundaries of five exons. Based on these sequences, five new NF1 exon-PCR assays have been developed, that could be useful for detecting new NF1 mutations. The genomic sequences were analyzed for...
MTGD: The Medicago truncatula genome database.
Medicago truncatula, a close relative of alfalfa (Medicago sativa), is a model legume used for studying symbiotic nitrogen fixation, mycorrhizal interactions and legume genomics. J. Craig Venter Institute (JCVI; formerly TIGR) has been involved in M. truncatula genome sequencing and annotation since 2002 and has maintained a web-based resource providing data to the community for this entire period. The website (http://www.MedicagoGenome.org) has seen major updates in the past year, where it...
San Diego Unified STEAM Leadership Series and the Salk Institute for Biological Studies Present: “The Places Your Imagination Takes You”—The 5th Annual Women in Biotech at the Salk
SAN DIEGO—On Wednesday, November 13th, the Salk Institute for Biological Studies will host the 5th Annual Women in Biotech with the San Diego Unified STEAM Leadership Series. Dr. Karen J. Nelson, president of the J. Craig Venter Institute will keynote, followed by an all-women panel from Illumina, the non-profit Match Your Need, and Salk Institute—300 young women from eight San Diego High schools will be welcomed by District Superintendent Cindy Marten, as part of the 18th event in...
Genomic Workshop for Native American College students
A Genomic Science Workshop was held last week (May 24-26, 2016) at the J Craig Venter Institute Rockville campus for a group of ten Native American college students. The students participated in two full-day intensive training activities learning how to study the “microbiome” of natural water sources. Each student had the chance to perform hands-on lab work including DNA isolation from an environmental water source, PCR of the 16S ribosomal RNA gene, and gel electrophoresis....
AGBT, Marco Island 2010
I just got back from AGBT in Marco Island, Florida and I am still in awe. As noted in the name, this conference highlights advances in both genome biology and technology. The biology seemed to be very human genome centric. Many of the talks presented full genome sequences of cancer genomes or familial cohorts. Some of the numbers that people threw around were shocking. It was only a short time ago that Craig Venter came out with the first personal genome, and now sequencing centers like...
Advocacy in Action: Effective Techniques for Shaping Science Policy
The American Society of Human Genetics will hold a workshop on “Effective Techniques for Shaping Science Policy,” led by J. Craig Venter Institute’s Anna Capria, October 16, 2024 at 12 PM EDT. Workshop details This workshop is for those passionate about human genetics who want to meaningfully impact the field through advocacy. You will gain foundational and practical skills to become an advocate, building on ASHG's ongoing efforts and highlighting available advocacy tools to...
Towards a comprehensive structural variation map of an individual human genome.
Several genomes have now been sequenced, with millions of genetic variants annotated. While significant progress has been made in mapping single nucleotide polymorphisms (SNPs) and small (