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JCVI La Jolla Breaks Ground
It is official! On Tuesday, September 20th JCVI officially broke ground on a new La Jolla, California sustainable lab, to be located directly on the campus of the University of California, San Diego. Craig Venter, JCVI Founder and President along with UCSD Chancellor Marye Anne Fox; Vice Chancellor for Health Sciences and Dean of the School of Medicine, David Brenner; Director of Scripps Institution of Oceanography and Vice Chancellor for Marine Sciences, Tony Haymet; and San Diego Mayor...
Generating a Library of Influenza a Virus Hemagglutanin and Neuraminidase Genes
Titas Bera, Anthony Bennici, Haley Hochstein, Karla M. Stucker, Suman R. Das, David E. Wentworth Virology Group, J. Craig Venter Institute, Rockville, MD 20850 Every year, five to twenty percent of the United States population is infected with seasonal influenza, making the construction of a seasonal vaccine of high importance. However, due to antigenic drift among seasonal influenza viruses, the vaccine strains need frequent updating. Antigenic drift occurs as the genes...
Potential Breakthroughs in Treating Oral Disease Through Better Understanding of the Oral Microbiome
Most people think of bacteria as the enemy, but scientists at the J. Craig Venter Institute (JCVI) are exploring ways to harness bacteria and phages (the viruses that infect bacteria) as a new way to fight infection. JCVI scientist, Anna Edlund, PhD, is leading one of our efforts to understand the human oral microbiome and learn what role bacteria play in both oral health and disease. Inflammatory gum disease (gingivitis/periodontal disease) and tooth decay are not only the two...
Use of the complete genome sequence information of Haemophilus influenzae strain Rd to investigate lipopolysaccharide biosynthesis.
The availability of the complete 1.83-megabase-pair sequence of the Haemophilus influenzae strain Rd genome has facilitated significant progress in investigating the biology of H.influenzae lipopolysaccharide (LPS), a major virulence determinant of this human pathogen. By searching the H. influenzae genomic database, with sequences of known LPS biosynthetic genes from other organisms, we identified and then cloned 25 candidate LPS genes. Construction of mutant strains and characterization...
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The J. Craig Venter Institute (JCVI) has several domain names which can be used to access JCVI web sites (Site or Sites). Such domain names include jcvi.org, tigr.org and other JCVI domain names. These Sites are controlled, operated and maintained by JCVI personnel in connection with JCVI business. Please read this statement carefully before accessing any Sites or conducting any transaction available at Sites. By using any of the Sites the user signifies that they have read this...
About Harinder Singh
Harinder Singh, PhD is a Staff Scientist in the Infectious Disease Department at the J. Craig Venter Institute (JCVI). Dr. Singh's area of research is mostly focused on various data analysis, data mining, development of prediction algorithm and databases and bioinformatics pipelines for the scientific community. Dr. Singh has significant experience in analyzing proteomics, metabolomics, expression, microbiome and metagenomics datasets using various bioinformatics pipelines. Dr.
Every Day is World Food Day at JCVI
World Food Day is a global initiative of the Food and Agriculture Organization (FAO) of the United Nations to ensure that people have access to enough high-quality food to lead active and healthy lives. After a period of decline, world hunger is on the rise again. Today, over 820 million people are suffering chronic undernourishment, according to the latest FAO 2018 State of Food Security and Nutrition in the World report. At JCVI we have several programs aimed at tackling world hunger....
About Julie Adelson
Julie Gross Adelson has devoted her career to the practice of health sciences and health care law as an in-house attorney. She is the Vice President and General Counsel for the J. Craig Venter Institute, a world leader in genomic research with more than 200 scientists and staff, and locations in Rockville, Maryland and La Jolla, California. Prior to joining the Institute in 2006, Ms.
Viral Synthetic Genomics to Engineer Large dsDNA Viruses
Viruses with large double-stranded DNA (dsDNA) genomes are a diverse group, which includes members that can infect a wide range of different hosts. Some of these viruses are important pathogens of humans and animals. Improving our ability to manipulate their genomes rapidly and accurately will increase our understanding of how these viruses replicate and cause disease and the likelihood of developing vaccines. Utilizing synthetic genomics tools developed by scientists at the J. Craig...