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Genomic and functional adaptation in surface ocean planktonic prokaryotes.
The understanding of marine microbial ecology and metabolism has been hampered by the paucity of sequenced reference genomes. To this end, we report the sequencing of 137 diverse marine isolates collected from around the world. We analysed these sequences, along with previously published marine prokaryotic genomes, in the context of marine metagenomic data, to gain insights into the ecology of the surface ocean prokaryotic picoplankton (0.1-3.0 μm size range). The results suggest that...
New Bioinformatics Hub at UChicago Enables Next-Gen Infectious Disease Research
The most valuable weapon against the next deadly disease outbreak may be data. Scientists aiming to stop or prevent the spread of viral or bacterial pathogens need rapid, comprehensive access to datasets on their genomics, structure, function and more, combined with computational tools to quickly analyze data and make predictions using artificial intelligence techniques. That critical service will be provided by the new Bacterial and Viral Bioinformatics Resource Center (BV-BRC),...
JCVI Women’s Center for Transformative Health
div.jcvi2-hero-text h1 { text-shadow: 0 0 55px #dd7d2c, 0 0 55px #dd7d2c; font-size: 50px; } h4[data-toggle="collapse"] img { height: 33px; transition: .33s; } h4[data-toggle="collapse"]:not(.collapsed) img { transform: scaleY(-1); } @media only screen and (max-width: 576px) { div.jcvi2-hero-text h1 { font-size: 36px; } } Women’s healthcare through precision science Building on Dr. Venter and JCVI’s pioneering work in human...
Infidelity of SARS-CoV Nsp14-exonuclease mutant virus replication is revealed by complete genome sequencing.
Most RNA viruses lack the mechanisms to recognize and correct mutations that arise during genome replication, resulting in quasispecies diversity that is required for pathogenesis and adaptation. However, it is not known how viruses encoding large viral RNA genomes such as the Coronaviridae (26 to 32 kb) balance the requirements for genome stability and quasispecies diversity. Further, the limits of replication infidelity during replication of large RNA genomes and how decreased fidelity...
Synthetic Genomics Vaccines, Inc. Hires Vaccine Executive Sammy J. Farah as President
LA JOLLA, CA — (September 29, 2011) — Synthetic Genomics Vaccines, Inc (SGVI), a privately held company focused on developing next generation vaccines using genomic sequencing and synthetic genomic technologies, announced today that Sammy J. Farah, Ph.D. has been appointed as president. Dr. Farah brings extensive vaccine expertise and over 15 years of scientific, business and executive management experience in the biotechnology industry to SGVI. "We are excited to have...
How to Bake a (Fungal) Turkey
From the kitchen of Stephanie Mounaud, Scientific Project Manager at JCVI Ingredients Media base (see media recipe) Agar Aspergillus terreus (multiple strains) Aspergillus niger Aspergillus fumigatus Aspergillus oryzae Pencillium marneffi Aspergillus flavus Instructions Start with a complex mixture of chemicals to make trace elements media. Sprinkle a little agar in there to get things...
JCVI Gala “2015: A Genome Odyssey” Celebrates Discovery
On October 24th, JCVI welcomed 200 guests to our third annual gala “2015: A Genome Odyssey.” Our annual gala has become a signature La Jolla event, and this year’s guests were not disappointed. Guests experienced an evening odyssey through land, sea and space interacting with JCVI scientists to learn first-hand what explorations are happening today. Proceeds from the gala will support JCVI’s Innovation Fund. As in past galas, our research was the focus. Guests learned how...
Battling Infectious Diseases with 3-D Structures
(CHICAGO) April 25, 2017 — An international team of scientists led by Northwestern University Feinberg School of Medicine has determined the 3-D atomic structure of more than 1,000 proteins that are potential drug and vaccine targets to combat some of the world’s most dangerous emerging and re-emerging infectious diseases. These experimentally determined structures have been deposited into the World-Wide Protein Data Bank, an archive supported by the National Institutes of Health...
Opentrons Announces New Robotics Education Initiative Demonstrating Commitment to Laboratory Automation for Students
BROOKLYN, N.Y. — Opentrons Labworks, Inc., a leader in lab automation and makers of accessible lab robotics, today announced the launch of Opentrons® for Education, an exclusive offering for educators to bring lab automation to the classroom. Opentrons is building a first-of-its-kind ecosystem for teaching with automation, which includes education pricing and support, along with access to a community of educators already teaching with Opentrons. Our goal is to make lab automation a...
President Honors Nation's Top Scientists and Innovators
President Obama today named nine eminent researchers as recipients of the National Medal of Science, and four inventors and one company as recipients of the National Medal of Technology and Innovation, the highest honors bestowed by the United States government on scientists, engineers, and inventors. The recipients will receive their awards on October 7 at a White House ceremony. The National Medal of Science was created by statute in 1959 and is administered for the White House by the...