Publications

Cancer causes & control : CCC. 2016-08-01; 27.8: 965-76.

Genetic variants in the mTOR pathway and interaction with body size and weight gain on breast cancer risk in African-American and European American women

Cheng TY, Shankar J, Zirpoli G, Roberts MR, Hong CC, Bandera EV, Ambrosone CB, Yao S

PMID: 27314662

Abstract

Positive energy imbalance and growth factors linked to obesity promote the phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin (mTOR) pathway. As the obesity-breast cancer associations differ between European American (EA) and African-American (AA) women, we investigated genetic variants in the mTOR pathway and breast cancer risk in these two racial groups.

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