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Scientists Decipher Genetic Code of Malaria Parasite
In a landmark contribution to the battle against malaria, scientists at TIGR and two other sequencing centers have deciphered the complex genetic code of the Plasmodium falciparum parasite that causes the deadliest form of the disease. In a related paper, a TIGR team also published a comparison of the genome with that of the model rodent malaria parasite, P. yoelii yoelii. And TIGR scientists played a role in sequencing the genome of the malaria-transmitting mosquito, Anophles gambiae.
Fraser Wins Lawrence Award
Secretary of Energy Spencer Abraham announced today that TIGR's president and director, Claire M. Fraser, Ph.D., will receive the E.O. Lawrence Award for her "contributions to genome analysis technology, its extension to the understanding of microbial diversity, and its application to human pathogens."
Towards the $1,000 Genome: "Hot Topic" Added to TIGR Genome Conference
Meeting Kicks Off With Keynote Lecture By Barry Bloom, Dean of Harvard's School of Public Health, Followed by Panel Discussion On New Sequencing Technologies
Genome of Potential Bioterror Agent Sequenced; Highlights Similarities Between Animal, Plant Pathogens
Scientists at TIGR, in collaboration with colleagues at three other research institutes, have determined the complete genomic sequence of Brucella suis, a bacterial pathogen and potential bioterrorism agent that could be targeted against humans or livestock.
Study Identifies Genetic Variation In Tuberculosis Strains
A TIGR comparison of the whole genomes of two strains of the bacterium that causes tuberculosis has found a surprising number of differences, indicating that genetic variation may be more extensive among Mycobacterium tuberculosis isolates than previously thought, and may play an important role in the development of the disease and of human immunity to it.
TIGR Offers Genomics Course
TIGR's genomics course for educators, which is designed to give high school biology teachers a thorough understanding of genomics, will be offered on Saturdays this fall, starting on October 19th.
Sequence Provides Insights Into An Emerging Pathogen's Virulence Mechanism, Allowing for Vaccine Development
An analysis of the whole genome sequence of Streptococcus agalactiae serotype V provides valuable insights into the virulence mechanism of the pathogen, which is a leading cause of pneumonia and meningitis in newborns and the source of life-threatening illnesses in a growing number of adults with deficient immune systems.
TIGR, IBEA, and TCAG to Create New High-Throughput Genomic Sequencing Facility
Center will be test bed for latest DNA sequencing and computing technology
Human sequencing to be conducted to better understand genetic variation
Mapping the Mouse Genome
An international research consortium that includes TIGR has published a comprehensive physical map of the mouse genome that provides an important resource for biomedical researchers. The TIGR team, led by Shaying Zhao, sequenced the BAC ends of the mouse genome.
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Scientist Spotlight: Todd Michael
A love of science began for Todd Michael, PhD when his 7th grade teacher had him write a report on tree leaves. After collecting different leaves and looking up their tree type, he realized that although all of the trees were similar, they grew different types of leaves. He was certain there...
Fighting Back Against Flu
The 1918 influenza pandemic, which affected 500 million people globally and caused 50-100 million deaths, was the most severe pandemic in recorded history. Over the course of the last 100 years, advances in science and medicine have provided the tools to address influenza much more...
Scientist Spotlight: Marcelo Freire
Marcelo Freire, an associate professor in the Genomic Medicine and Infectious Disease Department at the J. Craig Venter Institute (JCVI), is currently working on decoding immune-microbiome genes and interactions. Growing up in Brazil and a curious person by nature, he often found himself...
Tracking Enterovirus D68, Cause of a Polio-like Illness in Some Patients
The J. Craig Venter Institute (JCVI) has played a vital role in defining the diversity of contemporary strains of human enteroviruses by using state-of-the art sequencing technologies, bioinformatics analyses, and in vitro and in vivo modeling.
Every Day is World Food Day at JCVI
World Food Day is a global initiative of the Food and Agriculture Organization (FAO) of the United Nations to ensure that people have access to enough high-quality food to lead active and healthy lives. After a period of decline, world hunger is on the rise again. Today, over 820 million people...
Mold Is Everywhere and Impacts You
When most people think about mold or fungi, food spoilage, a damp basement, or mushrooms come to mind. What you may not realize is how pervasive this branch of life is. Fungi is everywhere, from the ground you walk on to the air you breathe, and accounts for an estimated 25% of all biomass...
Scientists Discover Genetic Basis for Toxic Algal Blooms
Scientists from the J. Craig Venter Institute (JCVI) and Scripps Institution of Oceanography at the University of California San Diego have discovered how certain types of algal blooms become toxic, producing a harmful substance known as domoic acid. Microscopic view of domoic acid...
Ocean Microplastics Explained
As we wrap up sampling in the waters off of Maine, Dr. Chris Dupont discusses how collections of plastic particles in the water – or “plastisphere” – may be harboring fish or human pathogens. There may also be microbes responsible for degrading plastic, which are being investigated....
JCVI Team Awarded Two Grants Under the NSF’s “Understanding the Rules of Life” Initiative
The first award, led by John Glass, PhD, for $1M, is focused on “Building and Modeling Synthetic Bacterial Cells.” The second award, led by Zaida Luthey-Schulten, PhD, at the University of Illinois, also for $1M, is titled “Balancing the Demands of a Minimal Cell,” and is focused on...
Dr. Venter at Sailors’ Scuttlebutt Lecture Series
Dr. Craig Venter was a guest speaker at the Whaling Museum in partnership with Nantucket Community Sailing as part of the Sailors’ Scuttlebutt Lecture Series. Dr. Venter's lecture was titled, "Oceans, Human Health and the Genomic Future" discussing the Global Ocean...
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Craig Venter: 20 years of decoding the human genome
The human genome is 99% decoded, the American geneticist Craig Venter announced two decades ago. What has the deciphering brought us since then?
Scientists in La Jolla Make Progress Understanding New Coronavirus Strain
Gene Drives: New and Improved
As the science advances, policy-makers and regulators need to develop responses that reflect the latest developments and the diversity of approaches and applications.
Pink shoes and a lab jacket: Finding your way as a female scientist
Women in science tell high school girls they, too, can change the world
PEOPLE IN YOUR NEIGHBORHOOD: Jazz piano in La Jolla scientist Clyde Hutchison’s DNA
How AI can help us decode immunity
Artificial intelligence and machine learning will be the keys to unraveling how the human immune system prevents and controls disease
Construction of an Escherichia coli genome with fewer codons sets records
The biggest synthetic genome so far has been made, with a smaller set of amino-acid-encoding codons than usual — raising the prospect of encoding proteins that contain unnatural amino-acid residues.
Public Health is the Next Big Thing at UC San Diego
Researchers have swapped the genome of gut germ E. coli for an artificial one
By creating a new genome, scientists could create organisms tailored to produce desirable compounds
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