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Genome Comparison of Four Campylobacter Strains Yields New Genetic Markers and Clues to Virulence
In a study that could benefit medical and food-safety research, scientists have used the tools of comparative genomics to find new clues about why some strains of the bacterium Campylobacter - which each year cause more than 400 million cases of gastrointestinal disease - are more virulent than others. The analysis is helping researchers develop more comprehensive detection methods for analyzing human and environmental isolates of the bacteria.
Microbe's Genome Reveals Insights Into Ocean Ecology
Unexpected findings about the genetic makeup of a marine microbe have given scientists a new perspective on how bacteria make a living in the ocean - a view that may prove useful in wider studies of marine ecology. The analysis by TIGR and collaborators of the DNA sequence of Silicibacter pomeroyi found that the metabolic strategies of marine bacterioplankton are more diverse and less conventional than previously thought.
Innovative Metagenomics Strategy Used To Study Oral Microbes
In an innovative new project, TIGR scientists and collaborators are using a metagenomics strategy to explore the complex mix of microbes in the human mouth. The research could help improve the diagnosis and treatment of periodontitis and other oral diseases.
Influenza Genome Sequencing Project Is Launched
TIGR will sequence a large number of human isolates of the influenza virus as part of a landmark influenza genome sequencing project announced Monday by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. The project aims to help scientists better understand how flu viruses evolve as they spread through the population.
TIGR and Virginia Tech Sign Memorandum for New Alliance
A new alliance between TIGR and Virginia Tech University is expected to enhance the Institute's computational and experimental capacity as well as enrich the university's basic research in the life sciences. The Memorandum of Understanding, announced Monday, anticipates joint research projects, shared use of related facilities, adjunct faculty appointments, and opportunities for students to participate in research.
TIGR's Fraser, Salzberg Honored As AAAS Fellows
TIGR President Claire M. Fraser and Senior Bioinformatics Director Steven L. Salzberg have been named as Fellows of the American Association for the Advancement of Science (AAAS) in recognition of their contributions to genomics and bioinformatics.
Computational Genomics Conference To Attract Leading Scientists
Comparative genomics, sequence assembly, gene expression analysis and genome annotation are among the hot topics to be discussed at the 7th annual Conference on Computational Genomics, which will be held October 21-24 in Reston, VA. The meeting is jointly sponsored by TIGR and The Jackson Laboratory.
J. Craig Venter Announces Consolidation of Three Research Organizations Into One New Not-For-Profit Organization — The J. Craig Venter Institute
The Center for Advancement of Genomics (TCAG), Institute for Biological Energy Alternatives (IBEA), and J. Craig Venter Science Foundation Joint Technology Center (JTC) consolidated to form J. Craig Venter Institute
Scientists Decipher Genome of Biothreat Pathogen
Highly Regulated Virulence Genes and Genomic Instability Found in the Infectious Horse Pathogen Burkholderia mallei
16TH International Genome Sequencing and Analysis Conference Features NIAID Director Anthony Fauci, Biologist E.O. Wilson and other Eminent Scientists
Conference in Washington, DC, highlights cutting-edge work in environmental genomics, human genomic medicine, biological energy production, evolutionary biology, and new sequencing technologies
GSAC also hosts half-day policy session on biodiversity and intellectual property issues
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Diatoms Have Found a Way to Pirate Bacterial Iron Sources
In large regions of the world’s oceans, photosynthesis struggles to operate because a key ingredient is missing. Many of the proteins involved in harvesting energy from sunlight require iron atoms to function, but iron is hard to find in seawater. Most of the ocean is far removed from...
The JCVI Genomic Frontier Fund
As we complete our 26th year as a private genomic research institution, we are still just as excited as we were in the very beginning to be making new discoveries, potentially ones that will change our society for the better. The knowledge gained from our study of DNA, or as Dr. Venter...
New Sequencing Technologies Enable Better and Faster Understanding of the Human Microbiome
Humans have trillions of different species of microorganisms living inside and on the human body. These microbes colonize on the skin, gut, oral cavity, vagina, internal organs, and circulating fluids, and are called the human microbiome. The human microbiome plays profound roles in health...
Human Microbiome Research has Massive Potential for Health Applications
Thirteen years ago, a team led by J. Craig Venter Institute President, Karen Nelson, Ph.D., published the first major human microbiome study, radically changing the way we look at human health and the role the microbes that inhabit each of us play in disease. This seminal publication...
Scientist Spotlight: Lauren Oldfield
Since high school, Lauren Oldfield, PhD found that science was her calling. It started with a love of reading encouraged by her mom and grandmother, both avid readers, and weekly trips to the public library. Books by Michael Crichton and Richard Preston were staples in her grandmother’s...
When Starved, Dangerous Oral Bacteria Hang On
J. Craig Venter Institute (JCVI) postdoctoral fellow, Jonathon Baker, PhD and a team of researchers from JCVI, University of Washington, the University of California, Los Angeles, and The Forsyth Institute recently published their findings from the first study to examine the ecological dynamics...
No More Needles! Using Microbiome and Synthetic Biology Advances to Better Treat Type 1 Diabetes
Learn about exciting advances made by JCVI researchers Yo Suzuki and John Glass who are on a quest to better understand and treat Type 1 Diabetes (T1D). Currently T1D is managed by injecting insulin to manage blood glucose levels. Drs. Suzuki and Glass want to change that by creating a...
How to Bake a (Fungal) Turkey
From the kitchen of Stephanie Mounaud, Scientific Project Manager at JCVI Ingredients Media base (see media recipe) Agar Aspergillus terreus (multiple strains) Aspergillus niger Aspergillus fumigatus Aspergillus oryzae...
Scientist Spotlight: Todd Michael
A love of science began for Todd Michael, PhD when his 7th grade teacher had him write a report on tree leaves. After collecting different leaves and looking up their tree type, he realized that although all of the trees were similar, they grew different types of leaves. He was certain there...
Fighting Back Against Flu
The 1918 influenza pandemic, which affected 500 million people globally and caused 50-100 million deaths, was the most severe pandemic in recorded history. Over the course of the last 100 years, advances in science and medicine have provided the tools to address influenza much more...
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Sailing the Seas in Search of Microbes
Projects aimed at collecting big data about the ocean’s tiniest life forms continue to expand our view of the seas.
What the Public Should Not Know
J. Craig Venter, PhD, argues scientists have “a moral obligation to communicate what they're doing to the public,” and that more studies deserve greater public criticism.
Scientists coax cells with the world’s smallest genomes to reproduce normally
The discovery could sharpen scientists’ understanding of which functions are crucial for normal cells and what the many mysterious genes in these organisms are doing
San Diego arts, health, science and youth groups to share $71M from Prebys Foundation
The J. Craig Venter Institute is the recipient of three awards totaling more than $1.5M to study SARS-CoV-2 and heart disease
Reflections on the 20th Anniversary of the First Publication of the Human Genome
A new wave of research is needed to make ample use of humanity’s “most wondrous map”
Scientists rush to determine if mutant strain of coronavirus will deepen pandemic
U.S. researchers have been slow to perform the genetic sequencing that will help clarify the situation
After saving countless lives, Nobel laureate Hamilton Smith retires as his own health falters
He has been a fixture in San Diego science for decades
The 'Wondrous Map': Charting of the Human Genome, 20 Years Later
Twenty years ago, President Bill Clinton announced completion of what was arguably one of the greatest advances of the modern era: the first draft sequence of the human genome.
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