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Scientists Decipher Genetic Code of Malaria Parasite
In a landmark contribution to the battle against malaria, scientists at TIGR and two other sequencing centers have deciphered the complex genetic code of the Plasmodium falciparum parasite that causes the deadliest form of the disease. In a related paper, a TIGR team also published a comparison of the genome with that of the model rodent malaria parasite, P. yoelii yoelii. And TIGR scientists played a role in sequencing the genome of the malaria-transmitting mosquito, Anophles gambiae.
Fraser Wins Lawrence Award
Secretary of Energy Spencer Abraham announced today that TIGR's president and director, Claire M. Fraser, Ph.D., will receive the E.O. Lawrence Award for her "contributions to genome analysis technology, its extension to the understanding of microbial diversity, and its application to human pathogens."
Towards the $1,000 Genome: "Hot Topic" Added to TIGR Genome Conference
Meeting Kicks Off With Keynote Lecture By Barry Bloom, Dean of Harvard's School of Public Health, Followed by Panel Discussion On New Sequencing Technologies
Genome of Potential Bioterror Agent Sequenced; Highlights Similarities Between Animal, Plant Pathogens
Scientists at TIGR, in collaboration with colleagues at three other research institutes, have determined the complete genomic sequence of Brucella suis, a bacterial pathogen and potential bioterrorism agent that could be targeted against humans or livestock.
Study Identifies Genetic Variation In Tuberculosis Strains
A TIGR comparison of the whole genomes of two strains of the bacterium that causes tuberculosis has found a surprising number of differences, indicating that genetic variation may be more extensive among Mycobacterium tuberculosis isolates than previously thought, and may play an important role in the development of the disease and of human immunity to it.
TIGR Offers Genomics Course
TIGR's genomics course for educators, which is designed to give high school biology teachers a thorough understanding of genomics, will be offered on Saturdays this fall, starting on October 19th.
Sequence Provides Insights Into An Emerging Pathogen's Virulence Mechanism, Allowing for Vaccine Development
An analysis of the whole genome sequence of Streptococcus agalactiae serotype V provides valuable insights into the virulence mechanism of the pathogen, which is a leading cause of pneumonia and meningitis in newborns and the source of life-threatening illnesses in a growing number of adults with deficient immune systems.
TIGR, IBEA, and TCAG to Create New High-Throughput Genomic Sequencing Facility
Center will be test bed for latest DNA sequencing and computing technology
Human sequencing to be conducted to better understand genetic variation
Mapping the Mouse Genome
An international research consortium that includes TIGR has published a comprehensive physical map of the mouse genome that provides an important resource for biomedical researchers. The TIGR team, led by Shaying Zhao, sequenced the BAC ends of the mouse genome.
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England, Here We Come!
In calm and clear conditions on May 11 Sorcerer II set sail for Plymouth, England. We enjoyed our brief stay in the Azores, but we were all excited to get to the U.K. and complete our North Atlantic crossing. As I mentioned in previous entries, we took samples near areas studied by...
Land Horta! The Sorcerer II on Faial Island, the Azores
We sailed into Horta on the island of Failal Saturday, May 9th around 1pm. The Sorcerer II crew was excited to visit the island but then again, we were just happy to walk on land and sleep in a bed that was not rolling from side to side! As usual when we arrive in a new port, we cleared...
North Atlantic Transit
After four days in Bermuda reconnecting with colleagues at BIOS and preparing for sampling across the North Atlantic, Sorcerer II departed on April 29th enroute to the port of Horta located on the island of Faial in the Azores. There are nine islands in the Azores archipelago which is...
Bermuda: Back to Where We Started
Sorcerer II arrived in Bermuda around 7 p.m. on Saturday April 25th after a five day, 1,000 mile sail from Fort Lauderdale, Florida. During the crossing, the crew experienced some challenging weather to say the least. Two samples were collected, and the CTD data confirmed what the J....
The Search for Environmental “Gems” Continues
As an original crew member of the Sorcerer II circumnavigation that began in 2003, I had not been sailing/sampling on the boat since September 2007. I arrived in Florida with a mixture of emotions. Although life on board can be tedious, I was excited to return and embark on this next leg of...
Back on Land
We arrive in Ft. Lauderdale and are all glad to be back on land for a few days. But we were also elated by the success of the first part of the expedition. This first journey was difficult because we had to deploy and test new equipment, to sample a diverse array of environments and...
Through the Canal
We are now out in the warm and saline Caribbean Sea, and the waters are an intense blue. The waters are so blue, there is very little in them: we drop the CTD and barely get 0.25 micrograms of Chlorophyll per liter all the way to the 50 meter mark. The clear waters of the Caribbean are very...
Miraflores Locks
We passed through the gigantic Miraflores locks on the Pacific side of the Panama Canal this morning, and now we are in front of the Smithsonian Tropical Research Station on Lake Gatun. The Sorcerer has sampled here on two other occasions, so to continue our time course evaluation, we ready the...
Going Green to Blue
As we round the southern most point on our trip we notice that the water has gone from blue to green, and that there appear to be surface current and eddies in the water. We decide to stop and have a look with the CTD. As we lower the instrument from the aft cockpit, we encounter a layer of...
Costa Rican Dome
In Nicaraguan waters is a regular spring upwelling event sometimes referred to as the Costa Rican dome. Winds blow across the Central American Isthmus near Lake Nicaragua and contribute to an upwelling of nutrient rich waters. These nutrients enable phytoplankton to grow, and as we approach the...
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Craig Venter: 20 years of decoding the human genome
The human genome is 99% decoded, the American geneticist Craig Venter announced two decades ago. What has the deciphering brought us since then?
Scientists in La Jolla Make Progress Understanding New Coronavirus Strain
Gene Drives: New and Improved
As the science advances, policy-makers and regulators need to develop responses that reflect the latest developments and the diversity of approaches and applications.
Pink shoes and a lab jacket: Finding your way as a female scientist
Women in science tell high school girls they, too, can change the world
PEOPLE IN YOUR NEIGHBORHOOD: Jazz piano in La Jolla scientist Clyde Hutchison’s DNA
How AI can help us decode immunity
Artificial intelligence and machine learning will be the keys to unraveling how the human immune system prevents and controls disease
Construction of an Escherichia coli genome with fewer codons sets records
The biggest synthetic genome so far has been made, with a smaller set of amino-acid-encoding codons than usual — raising the prospect of encoding proteins that contain unnatural amino-acid residues.
Public Health is the Next Big Thing at UC San Diego
Researchers have swapped the genome of gut germ E. coli for an artificial one
By creating a new genome, scientists could create organisms tailored to produce desirable compounds
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