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Genomics-Based Vaccine Could Prevent Deadly Cattle Disease
Every year, East Coast fever destroys the small farmer's dream of escaping poverty in Africa. Killing more than a million cattle and costing some $200 million annually, this tick-borne disease rages across a dozen countries in eastern and central Africa. Now, an international team of scientists has taken the first major step toward a vaccine to prevent East Coast fever. Their work, published in the February 13-17 early online edition of the Proceedings of the National Academy of Sciences, shows how genomics can generate pivotal new vaccines.
The J. Craig Venter Institute, The University of Washington, and The Johns Hopkins University Initiate Resequencing and Genotyping Projects to Help Identify Critical Disease Pathways
Research is Part of the National Heart, Lung, and Blood Institute's Complimentary Resequencing and Genotyping Program
UC San Diego Partners with Venter Institute to Build Community Cyberinfrastructure for Advanced Marine Microbial Ecology Research and Analysis
Gordon and Betty Moore Foundation Awards $24.5 Million Grant
2006 Summer Fellowship/Internship Information and application now available
Breaking the Mold: Research Teams Sequence Three Fungus Genomes
From garden compost to forest greenery, the mold Aspergillus fumigatus lurks across much of the world. Now, in the December 22 issue of the journal Nature, TIGR scientists and their collaborators report the mold's sequenced genome, along with the genomes of two relatives.
How Do Boxers Differ From Poodles? Researchers Collar Genomes.
As any dog lover knows, no two breeds are identical. Some dogs are perfect for sloppy kisses. Others make fierce guardians. Still others resemble tiny, fluffy toys. Now, two new studies by scientists at The Institute for Genomic Research (TIGR) and collaborators reveal the genomic differences beneath such canine characteristics.
Poison + Water = Hydrogen. New Microbial Genome Shows How.
New Microbial Genome Shows How "Take a pot of scalding water, remove all the oxygen, mix in a bit of poisonous carbon monoxide, and add a pinch of hydrogen gas. It sounds like a recipe for a witch's brew. It may be, but it is also the preferred environment for a microbe known as Carboxydothermus hydrogenoformans."
A Salty Tale: New Bacterial Genome Sequenced From Ancient Salterns
Tourists in Spain often stop to ogle the country's many saltwater lagoons, used to produce salt since Roman times. Scientists, too, admire these saltern crystallizers — and even more so, the microbes that manage to survive in such briny environs. Now, reporting in the November 28-December 2 early online edition of the Proceedings of the National Academy of Sciences, researchers at The Institute for Genomic Research and collaborators reveal the genome of one bacterium at home in the salty Spanish ponds.
First Big Influenza Genome Study Reveals Flu Evolution
Which Flu Did You Have? TIGR Scientists Survey Five New York Flu Seasons
Key Genetic Mutations in Brain Tumors Identified by Scientists from J. Craig Venter Institute, Ludwig Institute for Cancer Research, and The Johns Hopkins University School of Medicine
Sequencing of Receptor Tyrosine Kinases Reveals Three Novel Mutations
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North Atlantic Transit
After four days in Bermuda reconnecting with colleagues at BIOS and preparing for sampling across the North Atlantic, Sorcerer II departed on April 29th enroute to the port of Horta located on the island of Faial in the Azores. There are nine islands in the Azores archipelago which is...
Bermuda: Back to Where We Started
Sorcerer II arrived in Bermuda around 7 p.m. on Saturday April 25th after a five day, 1,000 mile sail from Fort Lauderdale, Florida. During the crossing, the crew experienced some challenging weather to say the least. Two samples were collected, and the CTD data confirmed what the J....
The Search for Environmental “Gems” Continues
As an original crew member of the Sorcerer II circumnavigation that began in 2003, I had not been sailing/sampling on the boat since September 2007. I arrived in Florida with a mixture of emotions. Although life on board can be tedious, I was excited to return and embark on this next leg of...
Back on Land
We arrive in Ft. Lauderdale and are all glad to be back on land for a few days. But we were also elated by the success of the first part of the expedition. This first journey was difficult because we had to deploy and test new equipment, to sample a diverse array of environments and...
Through the Canal
We are now out in the warm and saline Caribbean Sea, and the waters are an intense blue. The waters are so blue, there is very little in them: we drop the CTD and barely get 0.25 micrograms of Chlorophyll per liter all the way to the 50 meter mark. The clear waters of the Caribbean are very...
Miraflores Locks
We passed through the gigantic Miraflores locks on the Pacific side of the Panama Canal this morning, and now we are in front of the Smithsonian Tropical Research Station on Lake Gatun. The Sorcerer has sampled here on two other occasions, so to continue our time course evaluation, we ready the...
Going Green to Blue
As we round the southern most point on our trip we notice that the water has gone from blue to green, and that there appear to be surface current and eddies in the water. We decide to stop and have a look with the CTD. As we lower the instrument from the aft cockpit, we encounter a layer of...
Costa Rican Dome
In Nicaraguan waters is a regular spring upwelling event sometimes referred to as the Costa Rican dome. Winds blow across the Central American Isthmus near Lake Nicaragua and contribute to an upwelling of nutrient rich waters. These nutrients enable phytoplankton to grow, and as we approach the...
Gulf of Tehuantepec
We spend the day transiting the famously capricious Gulf of Tehuantepec, but today winds were calm, and we were able to cut across the bay in good time. At the southern end of the gulf is an underwater seamount, so we maneuver the Sorcerer over the seamount in hopes of encountering an...
Acapulco Harbor, Mexico
There probably isn’t a harbor in Mexico more impacted by tourism and development than Acapulco. We pull into the stunningly beautiful harbor and sample in front of an area of high rise hotels. The depth of the spot we sampled is only 40 feet, so we just take a surface water sample. Of...
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Craig Venter: 20 years of decoding the human genome
The human genome is 99% decoded, the American geneticist Craig Venter announced two decades ago. What has the deciphering brought us since then?
Scientists in La Jolla Make Progress Understanding New Coronavirus Strain
Gene Drives: New and Improved
As the science advances, policy-makers and regulators need to develop responses that reflect the latest developments and the diversity of approaches and applications.
Pink shoes and a lab jacket: Finding your way as a female scientist
Women in science tell high school girls they, too, can change the world
PEOPLE IN YOUR NEIGHBORHOOD: Jazz piano in La Jolla scientist Clyde Hutchison’s DNA
How AI can help us decode immunity
Artificial intelligence and machine learning will be the keys to unraveling how the human immune system prevents and controls disease
Construction of an Escherichia coli genome with fewer codons sets records
The biggest synthetic genome so far has been made, with a smaller set of amino-acid-encoding codons than usual — raising the prospect of encoding proteins that contain unnatural amino-acid residues.
Public Health is the Next Big Thing at UC San Diego
Researchers have swapped the genome of gut germ E. coli for an artificial one
By creating a new genome, scientists could create organisms tailored to produce desirable compounds
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