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Genome Analysis Sheds Light on Mobile DNA's Role in Pathogen's Resistance to Vancomycin
TIGR's sequencing and analysis of the genome of a vancomycin-resistant strain of Enterococcus faecalis has found that nearly a third of the genome consists of "mobile elements" -- segments of DNA that can jump between organisms or their chromosones -- that appear to play an important role in helping the bacterium quickly acquire resistance to drugs.
New Mobile Lab To Bolster Bioscience Education
The nation's newest and largest mobile laboratory, the MdBioLab, will be launched in early February to help Maryland high schools enhance their bioscience education programs. TIGR has partnered with MdBio, Inc., and the University of Maryland Biotechnology Institute to create this innovative non-profit project.
TIGR Offers Genomics Course
Rice Genome Sequence Announced By International Public Consortium
An international sequencing consortium that includes TIGR announced today that scientists have completed the assembly of an advanced, high-quality draft genome sequence of rice and made that data freely available. The sequence is an important new tool for agricultural and nutritional research involving one of the world's most important crops.
U.S.-German Research Consortium Sequences Genome of Versatile Soil Microbe
Pseudomonas putida Has Potential for Use in Bioremediation, Promoting Plant Growth and Fighting Plant Diseases
IBEA Receives $3 Million Dept. of Energy Grant for Synthetic Genome Development
Hamilton Smith, M.D., Nobel Laureate, Named Scientific Director of IBEA
Exploring Bacterial Branches of the Tree of Life
In an ambitious "phylogenomics" project, TIGR scientists have received an NSF grant to use whole genome sequence analysis to better understand the phylogenetic relationships among major bacterial groups.
Announcing the release of two packages useful in the analysis of shotgun sequence assembly data
TIGR evolutionary biologist Jonathan Eisen has been named as one of Esquire magazine's "Best and Brightest" innovators.
TIGR evolutionary biologist Jonathan Eisen has been named as one of Esquire magazine's "Best and Brightest" innovators. The list of 43 "emerging leaders who are reshaping our world" -- including nine scientists -- appears in the magazine's December issue.
TIGR Cracks Genome of Potential Bioremediation Agent
Scientists at TIGR and their collaborators have deciphered the genome sequence of the bacterium Shewanella oneidensis, which has great potential as a bioremediation agent to remove toxic metals such as chromium and uranium from the environment.
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Back on The Road, Mar Menor to Blanes, Spain
May 7th 2010 After a successful day of sampling in Mar Menor and a great local dinner of lobster paella, Chris and I loaded up the van and got back on the road early Friday morning. We had a 757 kilometer (470 miles) drive ahead of us to arrive in Blanes to meet with a team of collaborators...
The Green Lagoon — Sampling in Albufera de Valencia
During our sampling in Spain last year Chris and I met up with Francisco Rodriguez-Valera. Francisco had some great suggestions for sampling sites and one of them was Albufera de Valencia, a shallow hypertrophic fresh water lagoon, located just 30 minutes drive south of Valencia . When...
Road Sampling Starts in Mar Menor, Spain
Before sampling was to resume on Sorcerer II, a 2 week multiple-site road sampling trip was planned. Chris Dupont arrived in Valencia a day after me, in the next two days we would load up a giant rental van and hit the road. On Wednesday May 5th we drove the 322 kilometers (200 miles) from...
Return to Sorcerer II, The Mediterranean Season
Hello everyone! On May 2nd I flew from San Diego to rejoin Sorcerer II in Valencia Spain. Sorcerer II has been in Spain since our last sample in November, during that time her crew has been very busy upgrading systems and getting the rig certified. Sorcerer II is looking great and is ready for...
Looking for a Few Good Genomes (to sequence)!
The JCVI is one of three centers funded by the National Institutes of Allergy and Infectious Disease (NIAID) to provide sequencing and genotyping services to the infectious disease community. We are continually looking for researchers who would like to have organisms of research interest to...
Influences of trace metals on biological evolution
Scientists show how trace metal chemistry and global changes in oxygen have influenced the evolution of metalloproteins and the Eukaryotes A paper is being published in PNAS this week about how the varying abundance of trace metals in the environment has influenced biological...
JCVI Scientists Recognized by ASM
Drs. Karen E. Nelson and Kenneth H. Nealson are both being recognized by the American Academy of Microbiology (ASM) tomorrow, May 26, 2010. Karen has been elected to Fellowship in the ASM. She is one of seventy-eight new members that have been selected through a peer-review process based on...
Scientist Spotlight: Hamilton O. Smith and Clyde A. Hutchison III
Two of the superstars of science at the helm of the effort to make a synthetic cell (a cell with a completely man-made set of genetic instructions) are Hamilton Smith and Clyde Hutchison, or Ham and Clyde as they are affectionately known to colleagues. Since 2003 when they started working...
Happy DNA Day!
This past March, we had a great time participating in the science programs in San Diego. We ended the month with the SD Science Festival with over 30,000 participants. It was such a busy day - I forgot to take pictures. The venue was Petco Park with hundreds of exhibits and hands-on...
Recomb - Computational Proteomics
I recently attended the Recomb satellite conference on Computational Proteomics (downloads for talk and poster) in San Diego, CA. It was a kind of homecoming for me. I was a computational proteomics researcher at UCSD as a grad student with Vineet Bafna. Many of my classmates were still there,...
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Craig Venter: 20 years of decoding the human genome
The human genome is 99% decoded, the American geneticist Craig Venter announced two decades ago. What has the deciphering brought us since then?
Scientists in La Jolla Make Progress Understanding New Coronavirus Strain
Gene Drives: New and Improved
As the science advances, policy-makers and regulators need to develop responses that reflect the latest developments and the diversity of approaches and applications.
Pink shoes and a lab jacket: Finding your way as a female scientist
Women in science tell high school girls they, too, can change the world
PEOPLE IN YOUR NEIGHBORHOOD: Jazz piano in La Jolla scientist Clyde Hutchison’s DNA
How AI can help us decode immunity
Artificial intelligence and machine learning will be the keys to unraveling how the human immune system prevents and controls disease
Construction of an Escherichia coli genome with fewer codons sets records
The biggest synthetic genome so far has been made, with a smaller set of amino-acid-encoding codons than usual — raising the prospect of encoding proteins that contain unnatural amino-acid residues.
Public Health is the Next Big Thing at UC San Diego
Researchers have swapped the genome of gut germ E. coli for an artificial one
By creating a new genome, scientists could create organisms tailored to produce desirable compounds
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