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Scientists Decipher Genome of Bacterium that Helps Clean Up Major Groundwater Pollutants
Cryptococcus Study Sheds Light On How Fungi Cause Disease
Genome Comparison of Four Campylobacter Strains Yields New Genetic Markers and Clues to Virulence
In a study that could benefit medical and food-safety research, scientists have used the tools of comparative genomics to find new clues about why some strains of the bacterium Campylobacter - which each year cause more than 400 million cases of gastrointestinal disease - are more virulent than others. The analysis is helping researchers develop more comprehensive detection methods for analyzing human and environmental isolates of the bacteria.
Microbe's Genome Reveals Insights Into Ocean Ecology
Unexpected findings about the genetic makeup of a marine microbe have given scientists a new perspective on how bacteria make a living in the ocean - a view that may prove useful in wider studies of marine ecology. The analysis by TIGR and collaborators of the DNA sequence of Silicibacter pomeroyi found that the metabolic strategies of marine bacterioplankton are more diverse and less conventional than previously thought.
Innovative Metagenomics Strategy Used To Study Oral Microbes
In an innovative new project, TIGR scientists and collaborators are using a metagenomics strategy to explore the complex mix of microbes in the human mouth. The research could help improve the diagnosis and treatment of periodontitis and other oral diseases.
Influenza Genome Sequencing Project Is Launched
TIGR will sequence a large number of human isolates of the influenza virus as part of a landmark influenza genome sequencing project announced Monday by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. The project aims to help scientists better understand how flu viruses evolve as they spread through the population.
TIGR and Virginia Tech Sign Memorandum for New Alliance
A new alliance between TIGR and Virginia Tech University is expected to enhance the Institute's computational and experimental capacity as well as enrich the university's basic research in the life sciences. The Memorandum of Understanding, announced Monday, anticipates joint research projects, shared use of related facilities, adjunct faculty appointments, and opportunities for students to participate in research.
TIGR's Fraser, Salzberg Honored As AAAS Fellows
TIGR President Claire M. Fraser and Senior Bioinformatics Director Steven L. Salzberg have been named as Fellows of the American Association for the Advancement of Science (AAAS) in recognition of their contributions to genomics and bioinformatics.
Computational Genomics Conference To Attract Leading Scientists
Comparative genomics, sequence assembly, gene expression analysis and genome annotation are among the hot topics to be discussed at the 7th annual Conference on Computational Genomics, which will be held October 21-24 in Reston, VA. The meeting is jointly sponsored by TIGR and The Jackson Laboratory.
J. Craig Venter Announces Consolidation of Three Research Organizations Into One New Not-For-Profit Organization — The J. Craig Venter Institute
The Center for Advancement of Genomics (TCAG), Institute for Biological Energy Alternatives (IBEA), and J. Craig Venter Science Foundation Joint Technology Center (JTC) consolidated to form J. Craig Venter Institute
Scientists Decipher Genome of Biothreat Pathogen
Highly Regulated Virulence Genes and Genomic Instability Found in the Infectious Horse Pathogen Burkholderia mallei
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Straits of Messina Transect
Friday July 16th Today we woke up early and left our anchorage at Vulcano Island and headed to the Straits of Messina 20 miles away. The plan was to collect a sample at the north entrance, anchor for 5 hours to process the sample. Once the sample was completed then head to the middle of the...
Advance Access JCVI Metagenomics Reports Application Note
A significant JCVI informatics development is JCVI Metagenomics Reports, an open source Web 2.0 application designed to help scientists analyze and compare annotated metagenomics data sets. Users can download the application to upload and analyze their own metagenomics datasets. METAREP...
Naples Harbor Sampling
Thursday July 15th After getting some sleep at anchorage in Ischia island we sailed for a few hours to the main harbor in Naples. Over the years the Sorcerer II Expedition has collected samples in major ports around the world (Sydney, Halifax, Boston, Panama, Cape Town, just to...
Italian Sampling Continues-Unique Animal in Italian Waters!
Wednesday July 14th Monday July 12th we woke up early and left the anchorage in Capraia Island. We arrived at Ischia island at 5:00 a.m. on Wednesday the 14th. In those 48 hours we collected 6 samples. Two samples were collected in the Northern Tyrrhenian Sea, two samples were collected over...
Mediterranean Sampling Season Starts
Sunday July 11th 2010 On Thursday July 8th Sorcerer II set sail from Valencia Spain to start the Mediterranean season. Permits vary from country to country, Italy gave us 10 days to collect our samples, so we had to time our departure from Spain to fit our 10 day sampling window in Italy. As...
The Sorcerer II Sampling Process
July 6th In the blog about the media event I posted a few days back I put a link to the JCVI media page. On this page you can learn about our research goals, funders and past expeditions (more links on the right side of the page). Before we set out for this sampling season I wanted to...
Valencia, The Home Of Sorcerer II And Crew Since September 2009
July 5th Valencia is located about 140 miles (365 kilometers) from Barcelona. Valencia has a rich history and a distinct culture from other Spanish cities. I have only spent a few months here, but I wanted to share some of the highlights with you all before we set sail and start our...
High-performance comparative metagenomics
Are your carrying out large scale metagenomics analyses to identify differences among multiple sample sites? Are you looking for suitable analysis tools? If you have not yet found the right analysis tool, you may be interested in the latest beta version of JCVI...
Media Day Circus On Sorcerer II
June 23nd On Monday June 21st we announced the official start of the Mediterranean leg of the Sorcerer II Global Ocean Sampling Expedition. Dr. Venter took time from his busy schedule to fly into Valencia and attend the event as well as representatives from The Life Technology Foundation....
Genomics of the Indoor Air Environment
Most of our life is spent in indoors, well-buffered from the constant changes in temperature, humidity, wind and light which shape life outside our homes and offices. It seems intuitive that the types of microorganisms which inhabit our indoor environment must be different from those on the...
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Can CRISPR help stop African Swine Fever?
Gene editing could create a successful vaccine to protect against the viral disease that has killed close to 2 million pigs globally since 2021.
Getting Under the Skin
Amid an insulin crisis, one project aims to engineer microscopic insulin pumps out of a skin bacterium.
Planet Microbe
There are more organisms in the sea, a vital producer of oxygen on Earth, than planets and stars in the universe.
The Next Climate Change Calamity?: We’re Ruining the Microbiome, According to Human-Genome-Pioneer Craig Venter
In a new book (coauthored with Venter), a Vanity Fair contributor presents the oceanic evidence that human activity is altering the fabric of life on a microscopic scale.
Lessons from the Minimal Cell
“Despite reducing the sequence space of possible trajectories, we conclude that streamlining does not constrain fitness evolution and diversification of populations over time. Genome minimization may even create opportunities for evolutionary exploitation of essential genes, which are commonly observed to evolve more slowly.”
Even Synthetic Life Forms With a Tiny Genome Can Evolve
By watching “minimal” cells regain the fitness they lost, researchers are testing whether a genome can be too simple to evolve.
Privacy concerns sparked by human DNA accidentally collected in studies of other species
Two research teams warn that human genomic “bycatch” can reveal private information
Scientists Unveil a More Diverse Human Genome
The “pangenome,” which collated genetic sequences from 47 people of diverse ethnic backgrounds, could greatly expand the reach of personalized medicine.
First human ‘pangenome’ aims to catalogue genetic diversity
Researchers release draft results from an ongoing effort to capture the entirety of human genetic variation.
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