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Scientists Decipher Genetic Code of Malaria Parasite
In a landmark contribution to the battle against malaria, scientists at TIGR and two other sequencing centers have deciphered the complex genetic code of the Plasmodium falciparum parasite that causes the deadliest form of the disease. In a related paper, a TIGR team also published a comparison of the genome with that of the model rodent malaria parasite, P. yoelii yoelii. And TIGR scientists played a role in sequencing the genome of the malaria-transmitting mosquito, Anophles gambiae.
Fraser Wins Lawrence Award
Secretary of Energy Spencer Abraham announced today that TIGR's president and director, Claire M. Fraser, Ph.D., will receive the E.O. Lawrence Award for her "contributions to genome analysis technology, its extension to the understanding of microbial diversity, and its application to human pathogens."
Towards the $1,000 Genome: "Hot Topic" Added to TIGR Genome Conference
Meeting Kicks Off With Keynote Lecture By Barry Bloom, Dean of Harvard's School of Public Health, Followed by Panel Discussion On New Sequencing Technologies
Genome of Potential Bioterror Agent Sequenced; Highlights Similarities Between Animal, Plant Pathogens
Scientists at TIGR, in collaboration with colleagues at three other research institutes, have determined the complete genomic sequence of Brucella suis, a bacterial pathogen and potential bioterrorism agent that could be targeted against humans or livestock.
Study Identifies Genetic Variation In Tuberculosis Strains
A TIGR comparison of the whole genomes of two strains of the bacterium that causes tuberculosis has found a surprising number of differences, indicating that genetic variation may be more extensive among Mycobacterium tuberculosis isolates than previously thought, and may play an important role in the development of the disease and of human immunity to it.
TIGR Offers Genomics Course
TIGR's genomics course for educators, which is designed to give high school biology teachers a thorough understanding of genomics, will be offered on Saturdays this fall, starting on October 19th.
Sequence Provides Insights Into An Emerging Pathogen's Virulence Mechanism, Allowing for Vaccine Development
An analysis of the whole genome sequence of Streptococcus agalactiae serotype V provides valuable insights into the virulence mechanism of the pathogen, which is a leading cause of pneumonia and meningitis in newborns and the source of life-threatening illnesses in a growing number of adults with deficient immune systems.
TIGR, IBEA, and TCAG to Create New High-Throughput Genomic Sequencing Facility
Center will be test bed for latest DNA sequencing and computing technology
Human sequencing to be conducted to better understand genetic variation
Mapping the Mouse Genome
An international research consortium that includes TIGR has published a comprehensive physical map of the mouse genome that provides an important resource for biomedical researchers. The TIGR team, led by Shaying Zhao, sequenced the BAC ends of the mouse genome.
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USA Science & Engineering Festival
What a great weekend! Thousands of people attended the USA Science and Engineering Festival. There were exhibits and performances for everyone, every age and every interest! The DiscoverGenomics! Mobile Lab was there - Pennsylvania Avenue with several other mobile labs from across...
Second Leg of Greek Sampling
September 19th 2010 After we picked up our samples in Maliakos Gulf and changed Greek collaborators we sailed overnight to Psara Island to collect sample #30 on the sample map. Weather became an issue as we tried to collect samples site #26. The winds were blowing over 30 knots and seas were...
The Start of Greek Sampling and Rough Sampling Conditions!
September 15th 2010 Aegean Sea Map On September 10th we arrived in the northeastern Aegean Sea and docked in the city of Alexandroupolis. We spent a few hours dealing with customs which was not normal for the Mediterranean countries. Turns out that this area is well known for being an...
Tourist in Turkey
September 11th 2010 Our time in Turkey was relatively short, but we saw and learned a lot in that time. Our first stop was in Canakkale, it would have been an uneventful 1 night stop if it wasn’t for this…..Byron Hellespont Bicentenary Swim. This yearly race allows you to swim the 3...
Turkish Transect
September 10th 2010 Tonight we arrived in the Greek town of Alexandroupolis, which is located in northeast Aegean Sea. In the last 3 days we have collected 10 samples from 5 sites; it has been a long couple days! In the last blog I talked about the 2 sample sites in the Black Sea, since then...
Back To Sampling In The Black Sea and Rough Rough Weather
September 9th 2010 Hello everyone! I know it has been a long time since the last post from Sorcerer II. Let me take the time to explain…………..in early August we sailed to Greece. As I have mentioned in the past we have permits with each country to collect samples, these permits have...
Take home message of the 2010 Amebiasis Montreal Meeting: beware of who you kiss…
The Entamoeba community is a small and collegial one. Everyone knows everyone and everyone else wants to collaborate, and learn and do more to tackle down this neglected among neglected diseases. For many, the thought of an amoeba brings to memory Garry Larson’s The Far Side amorphous...
Entamoeba histolytica research presented at the Molecular Parasitology Meeting
Entamoeba histolytica causes invasive intestinal and extraintestinal infections, known as amoebiasis, in about 50 million people and still remains a significant cause of human death in developing countries. However, for unknown reasons, fewer than 10% of E. histolytica infections are...
Virtual Comparative Metagenomics
We have created an open virtualization format (OVF) package of JCVI's Metagenomics Reports (METAREP)- a high performance comparative metagenomics analysis tool. The software runs on a web server, retrieves data from two different database systems and uses R for statistical analysis. The new OVF...
Italy: Sites and Sailing
Saturday July 31st When I last wrote we had finished our 10 day sampling window in Italian waters. On Wednesday July 21st we arrived in Rome the same day Dr. Venter, Heather Kowalski, and Darwin the super boat dog had flown in from the states. We spent 3 days in Rome, most of the time was...
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Can CRISPR help stop African Swine Fever?
Gene editing could create a successful vaccine to protect against the viral disease that has killed close to 2 million pigs globally since 2021.
Getting Under the Skin
Amid an insulin crisis, one project aims to engineer microscopic insulin pumps out of a skin bacterium.
Planet Microbe
There are more organisms in the sea, a vital producer of oxygen on Earth, than planets and stars in the universe.
The Next Climate Change Calamity?: We’re Ruining the Microbiome, According to Human-Genome-Pioneer Craig Venter
In a new book (coauthored with Venter), a Vanity Fair contributor presents the oceanic evidence that human activity is altering the fabric of life on a microscopic scale.
Lessons from the Minimal Cell
“Despite reducing the sequence space of possible trajectories, we conclude that streamlining does not constrain fitness evolution and diversification of populations over time. Genome minimization may even create opportunities for evolutionary exploitation of essential genes, which are commonly observed to evolve more slowly.”
Even Synthetic Life Forms With a Tiny Genome Can Evolve
By watching “minimal” cells regain the fitness they lost, researchers are testing whether a genome can be too simple to evolve.
Privacy concerns sparked by human DNA accidentally collected in studies of other species
Two research teams warn that human genomic “bycatch” can reveal private information
Scientists Unveil a More Diverse Human Genome
The “pangenome,” which collated genetic sequences from 47 people of diverse ethnic backgrounds, could greatly expand the reach of personalized medicine.
First human ‘pangenome’ aims to catalogue genetic diversity
Researchers release draft results from an ongoing effort to capture the entirety of human genetic variation.
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