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Genome Analysis Sheds Light on Mobile DNA's Role in Pathogen's Resistance to Vancomycin
TIGR's sequencing and analysis of the genome of a vancomycin-resistant strain of Enterococcus faecalis has found that nearly a third of the genome consists of "mobile elements" -- segments of DNA that can jump between organisms or their chromosones -- that appear to play an important role in helping the bacterium quickly acquire resistance to drugs.
New Mobile Lab To Bolster Bioscience Education
The nation's newest and largest mobile laboratory, the MdBioLab, will be launched in early February to help Maryland high schools enhance their bioscience education programs. TIGR has partnered with MdBio, Inc., and the University of Maryland Biotechnology Institute to create this innovative non-profit project.
TIGR Offers Genomics Course
Rice Genome Sequence Announced By International Public Consortium
An international sequencing consortium that includes TIGR announced today that scientists have completed the assembly of an advanced, high-quality draft genome sequence of rice and made that data freely available. The sequence is an important new tool for agricultural and nutritional research involving one of the world's most important crops.
U.S.-German Research Consortium Sequences Genome of Versatile Soil Microbe
Pseudomonas putida Has Potential for Use in Bioremediation, Promoting Plant Growth and Fighting Plant Diseases
IBEA Receives $3 Million Dept. of Energy Grant for Synthetic Genome Development
Hamilton Smith, M.D., Nobel Laureate, Named Scientific Director of IBEA
Exploring Bacterial Branches of the Tree of Life
In an ambitious "phylogenomics" project, TIGR scientists have received an NSF grant to use whole genome sequence analysis to better understand the phylogenetic relationships among major bacterial groups.
Announcing the release of two packages useful in the analysis of shotgun sequence assembly data
TIGR evolutionary biologist Jonathan Eisen has been named as one of Esquire magazine's "Best and Brightest" innovators.
TIGR evolutionary biologist Jonathan Eisen has been named as one of Esquire magazine's "Best and Brightest" innovators. The list of 43 "emerging leaders who are reshaping our world" -- including nine scientists -- appears in the magazine's December issue.
TIGR Cracks Genome of Potential Bioremediation Agent
Scientists at TIGR and their collaborators have deciphered the genome sequence of the bacterium Shewanella oneidensis, which has great potential as a bioremediation agent to remove toxic metals such as chromium and uranium from the environment.
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Moving dirt at JCVI La Jolla
After celebrating the ground breaking of JCVI La Jolla, McCarthy Building Companies immediately got to work preparing the land for construction. First the crew set up a work area to house the staff and equipment needed for the project. The site was cleared and stabilized for construction...
Scientist Spotlight: Meet David Wentworth
During the height of the H1N1 Flu pandemic, David Wentworth was running a microbial genetics laboratory at the Wadsworth Center, New York State Department of Health (NYSDOH) where he was instrumental in developing a method to amplify influenza genomes regardless of strain using “universal...
2012 JCVI Internship Program Is Now Accepting New Applications
Wow! Another year has gone by. Its hard to think it is November - almost December with the warm weather we have been enjoying. However it did not start that way. The 2012 JCVI Internship Program is open to accept spring and summer applications. The application process...
JCVI La Jolla Breaks Ground
It is official! On Tuesday, September 20th JCVI officially broke ground on a new La Jolla, California sustainable lab, to be located directly on the campus of the University of California, San Diego. Craig Venter, JCVI Founder and President along with UCSD Chancellor Marye Anne Fox; Vice...
Evaluating Strain-level Variation of Key Acidogenic Species in Dental Plaque Biofilms
The characterization of the dental plaque microbiome, using traditional 16S rDNA profiling strategies, illustrates both the strengths and the limitations of this method. The central limitation of the 16S rDNA methodology is the inability to decipher strain-level variation within a...
Cataloguing the Gene Expression Patterns of Dental Plaque Biofilms: A Reference Dental Plaque Transcriptome
The RNA-Seq method has been widely adopted as an alternative to the use of DNA microarrays. In most contexts, the RNA-Seq method is implemented when a single reference organism is being studied. Our project endeavored to establish working methods to enable the generation of cDNA libraries that...
Surrogate Methods for Profiling Species of the Oral and Gut Microbiome
We engaged in an effort focused on alleviating a substantial barrier facing the human microbiome research community. While powerful, the 16S rDNA gene is insufficiently divergent to allow discrimination of many species and essentially no strains present within communities. The increasing costs...
The Mobile Lab Is Going to Sunny San Diego
Late one evening in January 2006, the mobile lab pulled into the parking lot at 9704 Medical Center Drive. It was such an exciting evening! Within a few days, we had all the lab supplies on it and began visiting students. The first school in the Washington Area was Patapsco Middle School in...
The Hill School: Day 2
The day started early Tuesday with first period. Thirty eager students arrived on the bus to determine the results of the amplification of the DNA they extracted the day before. The PCR ran overnight, copying part of a conserved gene in plants, RuBisCo, that can be used to...
The Hill School: Day 1
The day started early with reagent and lab preparation before we even left for school OR had coffee. We expected to do over 100 DNA Extractions as the first step in the DNA Barcoding. We arrived on campus as the first period was starting –we didn’t have class until after 9:00....
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Scientists Create the Smallest-Ever Moving Cell
Just two genes get tiny synthetic cells moving, offering clues to life’s evolution.
From Sequencing to Sailing: Three Decades of Adventure with Craig Venter
In a plenary public appearance at the Molecular and Precision Med TRI-CON event in San Diego, a relaxed Venter reflected on his career highlights, controversies and future priorities for genomic medicine.
Synthesizing life on the planet
What’s the smallest number of genes that cells need to grow and reproduce? Is it possible to synthesize minimal genomes and insert them into cells? What do minimal genomes teach us about life? An interview with John Glass, Ph.D.
Top scientists join forces to study leading theory behind long COVID
Several JCVI scientists will be contributing to the newly launched Long Covid Research Initiative — a collaboration of researchers, clinicians, and patients working to rapidly study and treat long Covid.
Hunting for deep-ocean plastics
Through the Woods Hole Oceanographic Institution, National Deep Submergence Facility, JCVI's Erin Garza, Ph.D. joins a deep sea expedition to search for ocean plastics aboard the HOV Alvin.
A journey to the center of our cells
Biologists are discovering the true nature of cells—and learning to build their own.
Dr. Hend Alqaderi on paving the way for women in science in the GCC
Hend Alqaderi, a JCVI collaborator and mentee to Marcelo Freire receives the L’Oréal-Unesco Women in Science award
Leonardo Da Vinci: New family tree spans 21 generations, 690 years, finds 14 living male descendants
The surprising results of a decade-long investigation by Alessandro Vezzosi and Agnese Sabato provide a strong basis for advancing a project researching Leonardo da Vinci's DNA.
Genome Research Papers on Meningococcal Recombination, Psoriasis Variants in China, More
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