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Scientists Decipher Genetic Code of Malaria Parasite
In a landmark contribution to the battle against malaria, scientists at TIGR and two other sequencing centers have deciphered the complex genetic code of the Plasmodium falciparum parasite that causes the deadliest form of the disease. In a related paper, a TIGR team also published a comparison of the genome with that of the model rodent malaria parasite, P. yoelii yoelii. And TIGR scientists played a role in sequencing the genome of the malaria-transmitting mosquito, Anophles gambiae.
Fraser Wins Lawrence Award
Secretary of Energy Spencer Abraham announced today that TIGR's president and director, Claire M. Fraser, Ph.D., will receive the E.O. Lawrence Award for her "contributions to genome analysis technology, its extension to the understanding of microbial diversity, and its application to human pathogens."
Towards the $1,000 Genome: "Hot Topic" Added to TIGR Genome Conference
Meeting Kicks Off With Keynote Lecture By Barry Bloom, Dean of Harvard's School of Public Health, Followed by Panel Discussion On New Sequencing Technologies
Genome of Potential Bioterror Agent Sequenced; Highlights Similarities Between Animal, Plant Pathogens
Scientists at TIGR, in collaboration with colleagues at three other research institutes, have determined the complete genomic sequence of Brucella suis, a bacterial pathogen and potential bioterrorism agent that could be targeted against humans or livestock.
Study Identifies Genetic Variation In Tuberculosis Strains
A TIGR comparison of the whole genomes of two strains of the bacterium that causes tuberculosis has found a surprising number of differences, indicating that genetic variation may be more extensive among Mycobacterium tuberculosis isolates than previously thought, and may play an important role in the development of the disease and of human immunity to it.
TIGR Offers Genomics Course
TIGR's genomics course for educators, which is designed to give high school biology teachers a thorough understanding of genomics, will be offered on Saturdays this fall, starting on October 19th.
Sequence Provides Insights Into An Emerging Pathogen's Virulence Mechanism, Allowing for Vaccine Development
An analysis of the whole genome sequence of Streptococcus agalactiae serotype V provides valuable insights into the virulence mechanism of the pathogen, which is a leading cause of pneumonia and meningitis in newborns and the source of life-threatening illnesses in a growing number of adults with deficient immune systems.
TIGR, IBEA, and TCAG to Create New High-Throughput Genomic Sequencing Facility
Center will be test bed for latest DNA sequencing and computing technology
Human sequencing to be conducted to better understand genetic variation
Mapping the Mouse Genome
An international research consortium that includes TIGR has published a comprehensive physical map of the mouse genome that provides an important resource for biomedical researchers. The TIGR team, led by Shaying Zhao, sequenced the BAC ends of the mouse genome.
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Sampling: US to the Azores
I’m off again on an ocean sampling voyage but this time instead of being onboard the JCVI’s Sorcerer II, I am onboard the R/V Endeavor as part of a multi-institution, international scientific sampling team that is headed from the US to the Azores. On Thursday August 22 we left Morehead...
Thule, Greenland - Day One
Arrived at Thule, Greenland after a 5 hr flight from Copenhagen. It was pretty interesting seeing a long line of people all getting on a flight that was headed to a part of the world that usually has less than 600 people there at any given time. Arrival was pretty straightforward, no jetway,...
Thule, Greenland - Day Three
Day three started with me missing breakfast. It seems that folks around here only eat breakfast between 5am and 8am. Today was a very rough day for sampling. About an hour drive to the area near the site, about a three-mile hike to one spot another half-mile hike to another spot...
The Next Generation Science Standards are Ready for Review
The second draft is ready for public comment through January 29th. Please be sure to take some time to review. http://www.nextgenscience.org/next-generation-science-standards
Plant Bioinformatics Workshop
JCVI recently held its 3rd Annual Plant Bioinformatics Workshop from July 15-19th. During the week-long workshop, 20 scientists from the Plant Research community visited JCVI and learned many aspects of Bioinformatics from the members of Chris Town’s Plant Genome group. Attendees included...
Carl Woese 1928-2012
Editor's Note: This post originally appeared on T. Taxus, December 31, 2012, by Jonathan Badger. Dr. Badger is an Assistant Professor in the Microbial and Environmental Genomics Group at the J. Craig Venter Institute in La Jolla, CA. Reprinted by permission. As you may have...
'Twas the night before Christmas
'Twas the night before Christmas, when all through the building All our creatures were stirring, even our mold; The dishes were placed in the incubator with prayer, In hopes that pure growth soon would be there; The scientists were nestled all...
JCVI Internship Information for 2013 Is Ready
We are now accepting applications for the 2013 Summer Internship Program. We are excited to be able to continue to inspire young scientists! Last year, we received 546 applications. Of which, thirty-one interns were selected to work in diverse areas....
Building a Solid Foundation
The JCVI La Jolla construction site has been busy since earthwork began in 2011. After grading the site to specified levels, a detailed excavation began to make room for the structural concrete footings, supporting slabs, and underground utilities. With all of the holes in just the right...
JCVI Viral Finishing Pipeline: a Winning Combination of Advanced Sequencing Technologies, Software Development and Automated Data Processing
JCVI viral projects are supported by the NIAID Genomic Sequencing Center for Infectious Disease (GSCID). The viral sequencing and finishing pipeline at JCVI combines next generation sequencing technologies with automated data processing. This allowed us to complete over 1,800 viral genomes...
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Can CRISPR help stop African Swine Fever?
Gene editing could create a successful vaccine to protect against the viral disease that has killed close to 2 million pigs globally since 2021.
Getting Under the Skin
Amid an insulin crisis, one project aims to engineer microscopic insulin pumps out of a skin bacterium.
Planet Microbe
There are more organisms in the sea, a vital producer of oxygen on Earth, than planets and stars in the universe.
The Next Climate Change Calamity?: We’re Ruining the Microbiome, According to Human-Genome-Pioneer Craig Venter
In a new book (coauthored with Venter), a Vanity Fair contributor presents the oceanic evidence that human activity is altering the fabric of life on a microscopic scale.
Lessons from the Minimal Cell
“Despite reducing the sequence space of possible trajectories, we conclude that streamlining does not constrain fitness evolution and diversification of populations over time. Genome minimization may even create opportunities for evolutionary exploitation of essential genes, which are commonly observed to evolve more slowly.”
Even Synthetic Life Forms With a Tiny Genome Can Evolve
By watching “minimal” cells regain the fitness they lost, researchers are testing whether a genome can be too simple to evolve.
Privacy concerns sparked by human DNA accidentally collected in studies of other species
Two research teams warn that human genomic “bycatch” can reveal private information
Scientists Unveil a More Diverse Human Genome
The “pangenome,” which collated genetic sequences from 47 people of diverse ethnic backgrounds, could greatly expand the reach of personalized medicine.
First human ‘pangenome’ aims to catalogue genetic diversity
Researchers release draft results from an ongoing effort to capture the entirety of human genetic variation.
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