06-Jul-2006
Press Release

MultiExperiment Viewer (MeV) 4.0 with Linear Expression Map (LEM) Module Released

July 6, 2006

Version 4.0 of the MultiExperiment Viewer has been released. New modules and feature upgrades include:

  • LEM - Linear Expression Map, mapping expression to chromosomal location
  • TEASE - Tree EASE, biological analysis for hierarchical tree branches
  • USC - Uncorrelated Shrunken Centroids, Multi-class classifier
  • BRIDGE - Bayesian Robust Inference for Differential Gene Expression
  • RAMA - Robust Analysis of MicroArrays, replicate analysis
  • Analysis Saving - A new robust implementation
  • Affymetrix(tm) Loading Support - new Affymetrix (tm) file input options

Of particular interest to prokaryotic and pathogen researchers in general is the Linear Expression Map module (LEM). The LEM module produces an expression viewer which maps gene expression to chromosomal location. The LEM allows one to visualize and track the expression of neighboring loci over the experimental conditions under study. Functional annotation can also be displayed which provides additional insights to sets of loci showing coherent patterns of expression. The map is highly customizable in appearance and has fine and course navigational controls to assist in stepping through the genome or chromosome being viewed. The LEM features also include options to view locus detail, options to view locus related spot annotation information, and the option to link to web resources for additional information about a selected locus. (See MeV's PDF manual page 142 for a full description of features and use, http://www.tm4.org/documentation/MeV_Manual_4_0.pdf)