HMM Summary Page: TIGR04537
Accession | TIGR04537 |
Name | encap_target |
Function | encapsulation C-terminal sorting signal |
Trusted Cutoff | 11.00 |
Domain Trusted Cutoff | 11.00 |
Noise Cutoff | 10.80 |
Domain Noise Cutoff | 10.80 |
Isology Type | domain |
HMM Length | 11 |
Author | Haft DH |
Entry Date | May 15 2014 11:28AM |
Last Modified | Sep 16 2014 4:02PM |
Comment | This model describes a diverse region of extremely small size (11 residues), so unavoidably there are both false-positives and false-negatives. All true hits should occur in proteins encoded next to an encapsulating protein (see PF04454), and should occur near the extreme C-terminus. Families previously known to have this domain on some members to mediate encapsulation include dye-decolorizing peroxidases and a ferritin-like protein, but (as this model helps show) there are others, including some hemerythrin family proteins and novel family TIGR04536. |
References | RN [1] RM PMID:23560779 RT Assembly in vitro of Rhodococcus jostii RHA1 encapsulin and peroxidase DypB to form a nanocompartment. RA Rahmanpour R, Bugg TD RL FEBS J. 2013 May;280(9):2097-104. doi: 10.1111/febs.12234. RN [2] RM PMID:19172747 RT Structural basis of enzyme encapsulation into a bacterial nanocompartment. RA Sutter M, Boehringer D, Gutmann S, Gunther S, Prangishvili D, Loessner MJ, Stetter KO, Weber-Ban E, Ban N RL Nat Struct Mol Biol. 2008 Sep;15(9):939-47. doi: 10.1038/nsmb.1473. |
Genome Property | GenProp0810: encapsulin proteinaceous organelle (HMM) |