HMM Summary Page: TIGR04439
| Accession | TIGR04439 |
| Name | histamin_N_OH |
| Function | putative histamine N-monooxygenase |
| Gene Symbol | basC |
| Trusted Cutoff | 700.00 |
| Domain Trusted Cutoff | 700.00 |
| Noise Cutoff | 550.00 |
| Domain Noise Cutoff | 550.00 |
| Isology Type | equivalog |
| EC Number | 1.14.13.- |
| HMM Length | 431 |
| Author | Haft DH |
| Entry Date | May 8 2013 5:49PM |
| Last Modified | May 8 2013 5:49PM |
| Comment | Members of this family are involved in synthesizing N-hydroxyhistamine as a precursor to acinetobactin, a siderophore found in Acinetobacter baumannii. Assuming histidine is first decarboxylated to histamine, then hydroxylated, members of this family are histamine N-monooxygenase. The putative histidine decarboxylase is found in the same biosynthetic cluster. |
| References | RN [1] RM PMID:15289555 RT Identification and transcriptional organization of a gene cluster involved in biosynthesis and transport of acinetobactin, a siderophore produced by Acinetobacter baumannii ATCC 19606T. RA Mihara K, Tanabe T, Yamakawa Y, Funahashi T, Nakao H, Narimatsu S, Yamamoto S RL Microbiology. 2004 Aug;150(Pt 8):2587-97. |