HMM Summary Page: TIGR04257
| Accession | TIGR04257 |
| Name | nanowire_3heme |
| Function | c(7)-type cytochrome triheme domain |
| Trusted Cutoff | 40.00 |
| Domain Trusted Cutoff | 40.00 |
| Noise Cutoff | 30.00 |
| Domain Noise Cutoff | 30.00 |
| Isology Type | domain |
| HMM Length | 75 |
| Author | Haft DH |
| Entry Date | Jan 3 2012 1:39PM |
| Last Modified | Feb 10 2012 10:37AM |
| Comment | This domain binds three hemes, and itself occurs as a repeating unit. It occurs, for instance, four times in the dodecaheme c-type cytochrome protein GSU_1996, whose crystal structure shows elongation and a nanowire-like arrangement of twelve hemes that could function in extracellular electron transport processes. |
| References | RN [1] RM PMID:21130881 RT Structure of a novel dodecaheme cytochrome c from Geobacter sulfurreducens reveals an extended 12 nm protein with interacting hemes. RA Pokkuluri PR, Londer YY, Duke NE, Pessanha M, Yang X, Orshonsky V, Orshonsky L, Erickson J, Zagyanskiy Y, Salgueiro CA, Schiffer M RL J Struct Biol. 2011 Apr;174(1):223-33. RN [2] RM PMID:19351328 RT Thermodynamic characterization of the redox centres in a representative domain of a novel c-type multihaem cytochrome. RA Morgado L, Fernandes AP, Londer YY, Pokkuluri PR, Schiffer M, Salgueiro CA RL Biochem J. 2009 May 27;420(3):485-92. |