HMM Summary Page: TIGR04253
| Accession | TIGR04253 |
| Name | mesacon_CoA_iso |
| Function | mesaconyl-CoA isomerase |
| Trusted Cutoff | 725.00 |
| Domain Trusted Cutoff | 725.00 |
| Noise Cutoff | 625.00 |
| Domain Noise Cutoff | 625.00 |
| Isology Type | equivalog |
| EC Number | 5.-.-.- |
| HMM Length | 403 |
| Author | Haft DH |
| Entry Date | Dec 23 2011 12:45PM |
| Last Modified | Feb 10 2012 10:37AM |
| Comment | Members of this protein family belong by homology to the family of CoA transferases. However, the characterized member from Chloroflexus aurantiacus appears to perform an intramolecular transfer, making it an isomerase. The enzyme converts mesaconyl-C1-CoA to mesaconyl-C4-CoA as part of the bicyclic 3-hydroxyproprionate pathway for carbon fixation. |
| References | RN [1] RM PMID:19955419 RT Identifying the missing steps of the autotrophic 3-hydroxypropionate CO2 fixation cycle in Chloroflexus aurantiacus. RA Zarzycki J, Brecht V, Muller M, Fuchs G RL Proc Natl Acad Sci U S A. 2009 Dec 15;106(50):21317-22. |