| Accession | TIGR04218 |
| Name | TOMM_plantaz |
| Function | ribosomal natural product, plantazolicin-class |
| Trusted Cutoff | 45.00 |
| Domain Trusted Cutoff | 40.00 |
| Noise Cutoff | 30.00 |
| Domain Noise Cutoff | 25.00 |
| Isology Type | subfamily |
| HMM Length | 43 |
| Author | Haft DH |
| Entry Date | Oct 26 2011 10:40AM |
| Last Modified | Oct 26 2011 2:17PM |
| Comment | Members of this protein family are precursors of TOMMs, that is, thizazole/oxazole-modified microcins. Members are about 42 residues in length, have a C-terminal region of extremely low complexity rich in Ser, and are often missed by ab initio gene callers. The plantazolicin from Bacillus amyloliquefaciens FZB42 is a peptide antibiotic effective against Bacillus anthracis. |
| References | RN [1]
RM PMID:21950656
RT Structure Determination and Interception of Biosynthetic Intermediates for the Plantazolicin Class of Highly Discriminating Antibiotics.
RA Molohon KJ, Melby JO, Lee J, Evans BS, Dunbar KL, Bumpus SB, Kelleher NL, Mitchell DA
RL ACS Chem Biol. 2011 Oct 6. |
