| Accession | TIGR04145 |
| Name | Firmicu_CTERM |
| Function | Firmicu-CTERM domain |
| Trusted Cutoff | 35.00 |
| Domain Trusted Cutoff | 35.00 |
| Noise Cutoff | 25.00 |
| Domain Noise Cutoff | 25.00 |
| Isology Type | hypoth_equivalog_domain |
| HMM Length | 45 |
| Author | Haft DH |
| Entry Date | Mar 23 2011 5:44PM |
| Last Modified | Feb 10 2012 12:42PM |
| Comment | This C-terminal domain is found only in the Firmicutes, where its presence is sporadically distributed. Proteins with this domain are most conserved in the C-terminal region, where the pattern of ending with a transmembrane domain resembles both the LPXTG (sortase target) and PEP-CTERM (exosortase target) domain structures. However, members occur exclusively in the presence of an exosortase-like protein XrtG (TIGR03110), a putative glycosyltransferase (TIGR03111), and a 6-pyruvoyl tetrahydropterin synthase-related protein (TIGR03112). |
| References | RN [1]
RM PMID:22037399
RT Archaeosortases and exosortases are widely distributed systems linking membrane transit with posttranslational modification.
RA Haft DH, Payne SH, Selengut JD
RL J Bacteriol. 2012 Jan;194(1):36-48. Epub 2011 Oct 28. |
| Genome Property | GenProp0669: protein sorting system, putative, exosortase G class (HMM) |
