HMM Summary Page: TIGR03999
| Accession | TIGR03999 |
| Name | thiol_BshA |
| Function | N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA |
| Gene Symbol | bshA |
| Trusted Cutoff | 273.70 |
| Domain Trusted Cutoff | 273.70 |
| Noise Cutoff | 173.85 |
| Domain Noise Cutoff | 173.85 |
| Isology Type | equivalog |
| EC Number | 2.4.1.- |
| HMM Length | 375 |
| Author | Haft DH |
| Entry Date | May 20 2010 4:52PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Members of this protein family are BshA, a glycosyltransferase required for bacillithiol biosynthesis. This enzyme combines UDP-GlcNAc and L-malate to form N-acetyl-alpha-D-glucosaminyl L-malate synthase. Bacillithiol is a low-molecular-weight thiol, an analog of glutathione and mycothiol, and is found largely in the Firmicutes. |
| References | RN [1] RM PMID:20308541 RT Biosynthesis and functions of bacillithiol, a major low-molecular-weight thiol in Bacilli. RA Gaballa A, Newton GL, Antelmann H, Parsonage D, Upton H, Rawat M, Claiborne A, Fahey RC, Helmann JD RL Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6482-6. |
| Genome Property | GenProp0927: bacillithiol biosynthesis (HMM) |