| Accession | TIGR03989 |
| Name | Rxyl_3153 |
| Function | NDMA-dependent alcohol dehydrogenase, Rxyl_3153 family |
| Trusted Cutoff | 440.00 |
| Domain Trusted Cutoff | 440.00 |
| Noise Cutoff | 360.00 |
| Domain Noise Cutoff | 360.00 |
| Isology Type | subfamily |
| EC Number | 1.1.99.36 |
| HMM Length | 370 |
| Author | Haft DH |
| Entry Date | Apr 19 2010 4:18PM |
| Last Modified | Apr 28 2014 11:57AM |
| Comment | This HMM describes a clade within the family PF00107 of zinc-binding dehydrogenases. The family PF00107 contains class III alcohol dehydrogenases, including enzymes designated S-(hydroxymethyl)glutathione dehydrogenase and NAD/mycothiol-dependent formaldehyde dehydrogenase. Members of the current family occur only in species that contain the very small protein mycofactocin (TIGR03969), a possible cofactor precursor, and radical SAM protein TIGR03962. We name this family for Rxyl_3153, where the lone member of the family co-clusters with these markers in Rubrobacter xylanophilus. |
| References | RN [1]
RM PMID:21223593
RT Bioinformatic evidence for a widely distributed, ribosomally produced electron carrier precursor, its maturation proteins, and its nicotinoprotein redox partners.
RA Haft DH
RL BMC Genomics. 2011 Jan 11;12(1):21.
RN [2]
RM PMID:10784035
RT Nicotinoprotein (NADH-containing) alcohol dehydrogenase from Rhodococcus erythropolis DSM 1069: an efficient catalyst for coenzyme-independent oxidation of a broad spectrum of alcohols and the interconversion of alcohols and aldehydes.
RA Schenkels P, Duine JA
RL Microbiology. 2000 Apr;146 ( Pt 4):775-85. |
| Genome Property | GenProp0917: mycofactocin system (HMM) |
