HMM Summary Page: TIGR03857
Accession | TIGR03857 |
Name | F420_MSMEG_2249 |
Function | probable F420-dependent oxidoreductase, MSMEG_2249 family |
Trusted Cutoff | 218.40 |
Domain Trusted Cutoff | 218.40 |
Noise Cutoff | 216.85 |
Domain Noise Cutoff | 216.85 |
Isology Type | hypoth_equivalog |
HMM Length | 329 |
Author | Haft DH |
Entry Date | Oct 9 2009 4:24PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | Coenzyme F420 has a limited phylogenetic distribution, including methanogenic archaea, Mycobacterium tuberculosis and related species, Colwellia psychrerythraea 34H, Rhodopseudomonas palustris HaA2, and others. Partial phylogenetic profiling identifies protein subfamilies, within the larger family called luciferase-like monooxygenanases (PF00296), that appear only in F420-positive genomes and are likely to be F420-dependent. This model describes a distinctive subfamily, found only in F420-biosynthesizing members of the Actinobacteria of the bacterial luciferase-like monooxygenase (LLM) superfamily. |
References | RN [1] RM PMID:20675471 RT Unexpected abundance of coenzyme F(420)-dependent enzymes in Mycobacterium tuberculosis and other actinobacteria. RA Selengut JD, Haft DH RL J Bacteriol. 2010 Nov;192(21):5788-98. |
Genome Property | GenProp0002: coenzyme F420 utilization (HMM) |