HMM Summary Page: TIGR03842
| Accession | TIGR03842 |
| Name | F420_CPS_4043 |
| Function | F420-dependent oxidoreductase, CPS_4043 family |
| Trusted Cutoff | 295.45 |
| Domain Trusted Cutoff | 295.45 |
| Noise Cutoff | 295.10 |
| Domain Noise Cutoff | 295.10 |
| Isology Type | hypoth_equivalog |
| HMM Length | 329 |
| Author | Haft DH |
| Entry Date | Sep 25 2009 1:16PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This HMM represents a family of putative F420-dependent oxidoreductases, fairly closely related to 5,10-methylenetetrahydromethanopterin reductase (mer, TIGR03555), both within the bacterial luciferase-like monoxygenase (LLM) family. A fairly deep split (to about 40 % sequence identity) in the present family separates a strictly Actinobacterial clade from an alpha/beta/gamma-proteobacterial clade, in which the member is often the only apparent F420-dependent LLM family member. The specific function, and whether Actinobacterial and Proteobacterial clades differ in function, are unknown. |
| References | RN [1] RM PMID:20675471 RT Unexpected abundance of coenzyme F(420)-dependent enzymes in Mycobacterium tuberculosis and other actinobacteria. RA Selengut JD, Haft DH RL J Bacteriol. 2010 Nov;192(21):5788-98. |
| Genome Property | GenProp0002: coenzyme F420 utilization (HMM) |