HMM Summary Page: TIGR03840
| Accession | TIGR03840 |
| Name | TMPT_Se_Te |
| Function | thiopurine S-methyltransferase, Se/Te detoxification family |
| Gene Symbol | tmpT |
| Trusted Cutoff | 223.20 |
| Domain Trusted Cutoff | 223.20 |
| Noise Cutoff | 189.85 |
| Domain Noise Cutoff | 189.85 |
| Isology Type | equivalog |
| EC Number | 2.1.1.67 |
| HMM Length | 213 |
| Author | Haft DH |
| Entry Date | Sep 23 2009 1:59PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Members of this family are thiopurine S-methyltransferase from a branch in which at least some member proteins can perform selenium methylation as a means to detoxify selenium, or perform a related detoxification of tellurium. Note that the EC number definition does not specify a particular thiopurine, but rather represents a class of activity. |
| References | RN [1] RM PMID:9565678 RT A tellurite-resistance genetic determinant from phytopathogenic pseudomonads encodes a thiopurine methyltransferase: evidence of a widely-conserved family of methyltransferases. RA Cournoyer B, Watanabe S, Vivian A RL Biochim Biophys Acta. 1998 Apr 29;1397(2):161-8. RN [2] RM PMID:15658983 RT Freshwater selenium-methylating bacterial thiopurine methyltransferases: diversity and molecular phylogeny. RA Favre-Bonte S, Ranjard L, Colinon C, Prigent-Combaret C, Nazaret S, Cournoyer B RL Environ Microbiol. 2005 Feb;7(2):153-64. |