Accession | TIGR03832 |
Name | Tyr_2_3_mutase |
Function | tyrosine 2,3-aminomutase |
Gene Symbol | cmdF |
Trusted Cutoff | 501.00 |
Domain Trusted Cutoff | 501.00 |
Noise Cutoff | 492.70 |
Domain Noise Cutoff | 492.70 |
Isology Type | equivalog |
EC Number | 5.4.3.6 |
HMM Length | 507 |
Gene Ontology Term | GO:0009058: biosynthetic process biological_process |
| GO:0050368: tyrosine 2,3-aminomutase activity molecular_function |
Author | Haft DH |
Entry Date | Sep 14 2009 2:39PM |
Last Modified | May 19 2014 1:45PM |
Comment | Members of this protein family are tyrosine 2,3-aminomutase. It is variable from member to member as to whether the (R)-beta-Tyr or (S)-beta-Tyr is the preferred product from L-Tyr. This enzyme tends to occur in secondary metabolite biosynthesis systems, as in the production of chondramides in Chondromyces crocatus. This class of enzyme has a prosthetic group, MIO (4-methylideneimidazol-5-one), that forms posttranslationally from an Ala-Ser-Gly motif. |
References | RN [1]
RM PMID:19222035
RT Discovery of additional members of the tyrosine aminomutase enzyme family and the mutational analysis of CmdF.
RA Krug D, Muller R
RL Chembiochem. 2009 Mar 2;10(4):741-50. |