| Accession | TIGR03804 |
| Name | para_beta_helix |
| Function | parallel beta-helix repeat |
| Trusted Cutoff | 19.45 |
| Domain Trusted Cutoff | 19.45 |
| Noise Cutoff | 15.60 |
| Domain Noise Cutoff | 15.60 |
| Isology Type | repeat |
| HMM Length | 44 |
| Author | Haft DH |
| Entry Date | Aug 13 2009 3:10PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This model represents a tandem pair of an approximately 22-amino acid (each) repeat homologous to the beta-strand repeats that stack in a right-handed parallel beta-helix in the periplasmic C-5 mannuronan epimerase, AlgA, of Pseudomonas aeruginosa. A homology domain consisting of a longer tandem array of these repeats is described in the SMART database as CASH (SM00722), and is found in many carbohydrate-binding proteins and sugar hydrolases. A single repeat is represented by SM00710. This TIGRFAMs model represents a flavor of the parallel beta-helix-forming repeat based on prokaryotic sequences only in its seed alignment, although it also finds many eukaryotic sequences. |
| References | RN [1]
RM PMID:11852237
RT CASH--a beta-helix domain widespread among carbohydrate-binding proteins.
RA Ciccarelli FD, Copley RR, Doerks T, Russell RB, Bork P
RL Trends Biochem Sci. 2002 Feb;27(2):59-62.
DR SMART; SM00722
DR SMART; SM00710 |
