| Accession | TIGR03693 |
| Name | ocin_ThiF_like |
| Function | putative thiazole-containing bacteriocin maturation protein |
| Trusted Cutoff | 561.90 |
| Domain Trusted Cutoff | 561.90 |
| Noise Cutoff | 142.30 |
| Domain Noise Cutoff | 142.30 |
| Isology Type | hypoth_equivalog |
| HMM Length | 637 |
| Mainrole Category | Cellular processes |
| Subrole Category | Toxin production and resistance |
| Gene Ontology Term | GO:0003674: molecular_function molecular_function |
| | GO:0005575: cellular_component cellular_component |
| | GO:0030152: bacteriocin biosynthetic process biological_process |
| Author | Haft DH |
| Entry Date | Nov 8 2008 10:30PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Members of this protein family are found in a three-gene operon in Bacillus anthracis and related Bacillus species, where the other two genes are clearly identified with maturation of a putative thiazole-containing bacteriocin precursor. While there is no detectable pairwise sequence similarity between members of this family and the proposed cyclodehydratases such as SagC of Streptococcus pyogenes (see family TIGR03603), both families show similarity through PSI-BLAST to ThiF, a protein involved in biosynthesis of the thiazole moiety for thiamine biosynthesis. This family, therefore, may contribute to cyclodehydratase function in heterocycle-containing bacteriocin biosyntheses. In Bacillus licheniformis ATCC 14580, the bacteriocin precursor gene is adjacent to the gene for this protein. |
