Accession | TIGR03666 |
Name | Rv2061_F420 |
Function | PPOX class probable F420-dependent enzyme, Rv2061 family |
Trusted Cutoff | 84.90 |
Domain Trusted Cutoff | 84.90 |
Noise Cutoff | 50.75 |
Domain Noise Cutoff | 50.75 |
Isology Type | subfamily |
EC Number | 1.-.-.- |
HMM Length | 132 |
Author | Haft DH |
Entry Date | Oct 20 2008 7:54AM |
Last Modified | Feb 14 2011 3:27PM |
Comment | A Genome Properties metabolic reconstruction for F420 biosynthesis shows that slightly over 10 percent of all prokaryotes with fully sequenced genomes, including about two thirds of the Actinomycetales, make F420. A variant of the Partial Phylogenetic Profiling algorithm, SIMBAL, shows that this protein likely binds F420 in a cleft similar to that in which the homologous enzyme pyridoxamine phosphate oxidase (PPOX) binds FMN. |
References | RN [1]
RM PMID:20675471
RT Unexpected abundance of coenzyme F(420)-dependent enzymes in Mycobacterium tuberculosis and other actinobacteria.
RA Selengut JD, Haft DH
RL J Bacteriol. 2010 Nov;192(21):5788-98. |
Genome Property | GenProp0002: coenzyme F420 utilization (HMM) |