| Accession | TIGR03400 |
| Name | 18S_RNA_Rcl1p |
| Function | 18S rRNA biogenesis protein RCL1 |
| Trusted Cutoff | 227.95 |
| Domain Trusted Cutoff | 227.95 |
| Noise Cutoff | 189.65 |
| Domain Noise Cutoff | 189.65 |
| Isology Type | equivalog |
| HMM Length | 360 |
| Author | Haft DH |
| Entry Date | Apr 26 2007 4:54PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Members of this strictly eukaryotic protein family are not RNA 3'-phosphate cyclase (6.5.1.4), but rather a homolog with a distinct function, found in the nucleolus and required for ribosomal RNA processing. Homo sapiens has both a member of this RCL (RNA terminal phosphate cyclase like) family and EC 6.5.1.4, while Saccharomyces has a member of this family only. |
| References | RN [1]
RM PMID: 10790377
RT Rcl1p, the yeast protein similar to the RNA 3'-phosphate cyclase, associates with U3 snoRNP and is required for 18S rRNA biogenesis.
RA Billy E, Wegierski T, Nasr F, Filipowicz W
RL EMBO J. 2000 May 2;19(9):2115-26. |
