| Accession | TIGR03298 |
| Name | argP |
| Function | transcriptional regulator, ArgP family |
| Gene Symbol | argP |
| Trusted Cutoff | 273.55 |
| Domain Trusted Cutoff | 273.55 |
| Noise Cutoff | 127.45 |
| Domain Noise Cutoff | 127.45 |
| Isology Type | subfamily |
| HMM Length | 292 |
| Mainrole Category | Cellular processes |
| Subrole Category | Toxin production and resistance |
| Gene Ontology Term | GO:0003677: DNA binding molecular_function |
| | GO:0005737: cytoplasm cellular_component |
| | GO:0006350: transcription biological_process |
| | GO:0008156: negative regulation of DNA replication biological_process |
| | GO:0016564: transcription repressor activity molecular_function |
| | GO:0043200: response to amino acid stimulus biological_process |
| Author | Haft DH |
| Entry Date | Jan 31 2007 2:25PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | ArgP used to be known as IciA. ArgP is a positive regulator of argK. It is a negative autoregulator in presence of arginine. It competes with DnaA for oriC iteron (13-mer) binding. It activates dnaA and nrd transcription. It has been demonstrated to be part of the pho regulon (PMID:10589831). ArgP mutants convey canavanine (an L-arginine structural homolog) sensitivity (PMID: 15150242). |
