| Accession | TIGR03244 |
| Name | arg_catab_AstA |
| Function | arginine N-succinyltransferase |
| Gene Symbol | astA |
| Trusted Cutoff | 391.00 |
| Domain Trusted Cutoff | 391.00 |
| Noise Cutoff | 358.20 |
| Domain Noise Cutoff | 358.20 |
| Isology Type | equivalog |
| EC Number | 2.3.1.109 |
| HMM Length | 336 |
| Mainrole Category | Energy metabolism |
| Subrole Category | Amino acids and amines |
| Gene Ontology Term | GO:0006527: arginine catabolic process biological_process |
| | GO:0008791: arginine N-succinyltransferase activity molecular_function |
| Author | Haft DH |
| Entry Date | Jan 6 2007 9:48AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | In many bacteria, the arginine succinyltransferase (ast) pathway operon consists of five genes, including this protein, arginine N-succinyltransferase (EC 2.3.1.109). In a few species, such as Pseudomonas aeruginosa, the member of this family is encoded adjacent to a paralog, and the two polypeptides form a heterodimeric enzyme, active on both arginine and ornithine. In such species, this polypeptide may be treated as the beta subunit of an enzyme that may be named either arginine N-succinyltransferase (AST) or arginine and orthithine N-succinyltransferase (AOST). |
| References | RN [1]
RM PMID: 9393691
RT Cloning and characterization of the aru genes encoding enzymes of the catabolic arginine succinyltransferase pathway in Pseudomonas aeruginosa.
RA Itoh Y
RL J Bacteriol. 1997 Dec;179(23):7280-90. |
| Genome Property | GenProp0309: arginine catabolism to glutamate via arginine succinyltransferase (AST) (HMM) |
