Accession | TIGR03132 |
Name | malonate_mdcB |
Function | triphosphoribosyl-dephospho-CoA synthase MdcB |
Gene Symbol | mdcB |
Trusted Cutoff | 282.35 |
Domain Trusted Cutoff | 282.35 |
Noise Cutoff | 279.65 |
Domain Noise Cutoff | 279.65 |
Isology Type | equivalog |
EC Number | 2.4.2.52 |
HMM Length | 272 |
Mainrole Category | Biosynthesis of cofactors, prosthetic groups, and carriers |
Subrole Category | Other |
Gene Ontology Term | GO:0019361: 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA biosynthetic process biological_process |
| GO:0046917: triphosphoribosyl-dephospho-CoA synthase activity molecular_function |
Author | Haft DH |
Entry Date | Oct 31 2006 3:06PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | This protein acts in cofactor biosynthesis, preparing the coenzyme A derivative that becomes attached to the malonate decarboxylase acyl carrier protein (or delta subunit). The closely related protein CitG of citrate lyase produces the same molecule, but the two families are nonetheless readily separated. |
References | RN [1]
RM PMID: 11052675
RT Biosynthesis of triphosphoribosyl-dephospho-coenzyme A, the precursor of the prosthetic group of malonate decarboxylase.
RA Hoenke S, Wild MR, Dimroth P
RL Biochemistry. 2000 Oct 31;39(43):13223-32. |
Genome Property | GenProp0674: malonate decarboxylase (HMM) |