| Accession | TIGR02883 |
| Name | spore_cwlD |
| Function | N-acetylmuramoyl-L-alanine amidase CwlD |
| Gene Symbol | cwlD |
| Trusted Cutoff | 221.55 |
| Domain Trusted Cutoff | 221.55 |
| Noise Cutoff | 142.10 |
| Domain Noise Cutoff | 142.10 |
| Isology Type | equivalog |
| EC Number | 3.5.1.28 |
| HMM Length | 189 |
| Mainrole Category | Cell envelope |
| Subrole Category | Biosynthesis and degradation of murein sacculus and peptidoglycan |
| Gene Ontology Term | GO:0008745: N-acetylmuramoyl-L-alanine amidase activity molecular_function |
| | GO:0030436: asexual sporulation biological_process |
| Author | Haft DH |
| Entry Date | Mar 9 2006 4:06PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Members of this protein family are the CwlD family of N-acetylmuramoyl-L-alanine amidase. This family has been called the germination-specific N-acetylmuramoyl-L-alanine amidase. CwlD is required, along with the putative deactylase PdaA, to make muramic delta-lactam, a novel peptidoglycan constituent found only in spores. CwlD mutants show a germination defect. |
| References | RN [1]
RM 14679227
RT Production of muramic delta-lactam in Bacillus subtilis spore peptidoglycan.
RA Gilmore ME, Bandyopadhyay D, Dean AM, Linnstaedt SD, Popham DL.
RL J Bacteriol. 2004 Jan;186(1):80-9. |
