| Accession | TIGR02875 |
| Name | spore_0_A |
| Function | sporulation transcription factor Spo0A |
| Gene Symbol | spo0A |
| Trusted Cutoff | 200.00 |
| Domain Trusted Cutoff | 195.00 |
| Noise Cutoff | 180.00 |
| Domain Noise Cutoff | 180.00 |
| Isology Type | equivalog |
| HMM Length | 262 |
| Mainrole Category | Cellular processes |
| Subrole Category | Sporulation and germination |
| Gene Ontology Term | GO:0000156: two-component response regulator activity molecular_function |
| | GO:0000160: two-component signal transduction system (phosphorelay) biological_process |
| | GO:0006355: regulation of transcription, DNA-dependent biological_process |
| | GO:0030436: asexual sporulation biological_process |
| | GO:0042173: regulation of sporulation resulting in formation of a cellular spore biological_process |
| Author | Haft DH |
| Entry Date | Mar 8 2006 9:51AM |
| Last Modified | Mar 6 2011 12:57PM |
| Comment | Spo0A, the stage 0 sporulation protein A, is a transcription factor critical for the initiation of sporulation. It contains a response regulator receiver domain (PF00072). In Bacillus subtilis, it works together with response regulator Spo0F and the phosphotransferase Spo0B, both of which are missing from at least some sporulating species and thus not part of the endospore forming bacteria minimal gene set. Spo0A, however, is universal among endospore-forming species. |
| References | DR PFAM; PF00072; Response_reg
RN [1]
RM 16420367
RT Phosphorylation and functional analysis of the sporulation initiation factor Spo0A from Clostridium botulinum.
RA Worner K, Szurmant H, Chiang C, Hoch JA.
RL Mol Microbiol. 2006 Feb;59(3):1000-12. |
| Genome Property | GenProp0610: endospore formation marker gene set (HMM) |
