| Accession | TIGR02862 |
| Name | spore_BofA |
| Function | pro-sigmaK processing inhibitor BofA |
| Gene Symbol | bofA |
| Trusted Cutoff | 53.35 |
| Domain Trusted Cutoff | 53.35 |
| Noise Cutoff | 34.00 |
| Domain Noise Cutoff | 34.00 |
| Isology Type | subfamily |
| HMM Length | 83 |
| Mainrole Category | Cellular processes |
| Subrole Category | Sporulation and germination |
| Gene Ontology Term | GO:0016020: membrane cellular_component |
| | GO:0030436: asexual sporulation biological_process |
| Author | Haft DH |
| Entry Date | Mar 3 2006 1:59PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Members of this protein family are found only in endospore-forming bacteria, such as Bacillus subtilis and Clostridium tetani. Among such bacteria, it appears only Symbiobacterium thermophilum lacks a member of this family. The protein, designated BofA, is an integral membrane protein that regulates the proteolytic activation of the RNA polymerase sigma factor K. |
| References | RN [1]
RM 11959848
RT A sporulation membrane protein tethers the pro-sigmaK processing enzyme to its inhibitor and dictates its subcellular localization.
RA Rudner DZ, Losick R.
RL Genes Dev. 2002 Apr 15;16(8):1007-18. |
