HMM Summary Page: TIGR02801

AccessionTIGR02801
NametolR
Functionprotein TolR
Gene SymboltolR
Trusted Cutoff127.30
Domain Trusted Cutoff127.30
Noise Cutoff121.75
Domain Noise Cutoff121.75
Isology Typeequivalog
HMM Length129
Mainrole CategoryTransport and binding proteins
Subrole CategoryOther
Gene Ontology TermGO:0015078: hydrogen ion transmembrane transporter activity molecular_function
GO:0015992: proton transport biological_process
GO:0016044: cellular membrane organization biological_process
GO:0031237: intrinsic to external side of plasma membrane, in periplasmic space cellular_component
AuthorHaft DH
Entry DateJan 20 2006 3:28PM
Last ModifiedFeb 14 2011 3:27PM
CommentThe model describes the inner membrane protein TolR, part of the TolR/TolQ complex that transduces energy from the proton-motive force, through TolA, to an outer membrane complex made up of TolB and Pal (peptidoglycan-associated lipoprotein). The complex is required to maintain outer membrane integrity, and defects may cause a defect in the import of some organic compounds in addition to the resulting morphologic. While several gene pairs homologous to talR and tolQ may be found in a single genome, but the scope of this model is set to favor finding only bone fide TolR, supported by operon structure as well as by score.
Genome PropertyGenProp0542: Tol-Pal system (HMM)