Accession | TIGR02798 |
Name | ligK_PcmE |
Function | 4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase |
Gene Symbol | ligK |
Trusted Cutoff | 304.50 |
Domain Trusted Cutoff | 304.50 |
Noise Cutoff | 215.55 |
Domain Noise Cutoff | 215.55 |
Isology Type | equivalog |
EC Number | 4.1.-.- 4.1.1.3 |
HMM Length | 222 |
Author | Haft DH |
Entry Date | Jan 20 2006 11:46AM |
Last Modified | Feb 14 2011 3:27PM |
Comment | Members of this protein family 4-carboxy-4-hydroxy-2-oxoadipate aldolase, also called 4-oxalocitramalate aldolase. This enzyme of the protocatechuate 4,5-cleavage pathway converts its substrate to pyruvate plus oxaloacetate. Protocatechuate is an intermediate in many pathways for degrading aromatic compounds, including lignin, fluorene, etc. Hara, et al. showed the LigK gene was not only a 4-carboxy-4-hydroxy-2-oxoadipate aldolase but also the enzyme of the following step, oxaloacetate decarboxylase. |
References | RN [1]
RM 12486039
RT Characterization of the 4-carboxy-4-hydroxy-2-oxoadipate aldolase gene and operon structure of the protocatechuate 4,5-cleavage pathway genes in Sphingomonas paucimobilis SYK-6.
RA Hara H, Masai E, Miyauchi K, Katayama Y, Fukuda M.
RL J Bacteriol. 2003 Jan;185(1):41-50. |