HMM Summary Page: TIGR02723
Accession | TIGR02723 |
Name | phenyl_P_alpha |
Function | phenylphosphate carboxylase, alpha subunit |
Gene Symbol | ppcA |
Trusted Cutoff | 564.60 |
Domain Trusted Cutoff | 564.60 |
Noise Cutoff | 244.30 |
Domain Noise Cutoff | 244.30 |
Isology Type | equivalog |
EC Number | 4.1.1.- |
HMM Length | 485 |
Mainrole Category | Energy metabolism |
Subrole Category | Anaerobic |
Author | Haft DH |
Entry Date | Dec 7 2005 11:13AM |
Last Modified | Feb 14 2011 3:27PM |
Comment | Members of this protein family are the alpha subunit of phenylphosphate carboxylase. Phenol (methyl-benzene) is converted to phenylphosphate, then para-carboxylated by this four-subunit enzyme, with the release of phosphate, to 4-hydroxybenzoate. The enzyme contains neither biotin nor thiamin pyrophosphate. This alpha subunit is homologous to the beta subunit and, more broadly, to UbiD family decarboxylases. |
References | RM 15231788 RT Phenylphosphate carboxylase: a new C-C lyase involved in anaerobic phenol metabolism in Thauera aromatica. RA Schuhle K, Fuchs G. RL J Bacteriol. 2004 Jul;186(14):4556-67. |