Accession | TIGR02718 |
Name | sider_RhtX_FptX |
Function | siderophore transporter, RhtX/FptX family |
Trusted Cutoff | 356.15 |
Domain Trusted Cutoff | 356.15 |
Noise Cutoff | 217.80 |
Domain Noise Cutoff | 217.80 |
Isology Type | subfamily |
HMM Length | 390 |
Mainrole Category | Transport and binding proteins |
Subrole Category | Cations and iron carrying compounds |
Gene Ontology Term | GO:0015891: siderophore transport biological_process |
| GO:0042927: siderophore transporter activity molecular_function |
Author | Haft DH |
Entry Date | Dec 2 2005 10:38PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | RhtX from Sinorhizobium meliloti 2011 and FptX from Pseudomonas aeruginosa appear to be single polypeptide transporters, from the major facilitator family (see PF07690) for import of siderophores as a means to import iron. This function was suggested by proximity to siderophore biosynthesis genes and then confirmed by study of knockout and heterologous expression phenotypes. |
References | DR PFAM; PF07690; MFS_1; transporter, major facilitator family
RM 15126460
RT Identification of rhtX and fptX, novel genes encoding proteins that show homology and function in the utilization of the siderophores rhizobactin 1021 by Sinorhizobium meliloti and pyochelin by Pseudomonas aeruginosa, respectively.
RA Cuiv PO, Clarke P, Lynch D, O'Connell M.
RL J Bacteriol. 2004 May;186(10):2996-3005. |