HMM Summary Page: TIGR02651
Accession | TIGR02651 |
Name | RNase_Z |
Function | ribonuclease Z |
Gene Symbol | rnz |
Trusted Cutoff | 292.95 |
Domain Trusted Cutoff | 292.95 |
Noise Cutoff | 147.90 |
Domain Noise Cutoff | 147.90 |
Isology Type | equivalog |
EC Number | 3.1.26.11 |
HMM Length | 302 |
Mainrole Category | Transcription |
Subrole Category | RNA processing |
Gene Ontology Term | GO:0016891: endoribonuclease activity, producing 5'-phosphomonoesters molecular_function |
GO:0042779: tRNA 3'-trailer cleavage biological_process | |
Author | Haft DH |
Entry Date | Aug 30 2005 4:59PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | Processing of the 3-prime end of tRNA precursors may be the result of endonuclease or exonuclease activity, and differs in different species. Member of this family are ribonuclease Z, a tRNA 3-prime endonuclease that processes tRNAs to prepare for addition of CCA. In species where all tRNA sequences already have the CCA tail, such as E. coli, the need for such an enzyme is unclear. Protein similar to the E. coli enzyme, matched by TIGRFAMs HMM TIGR02649, are designated ribonuclease BN. |
References | DR TIGRFAMS; TIGR02649; exception; ribonuclease BN DR HAMAP; MF_01818; 185 of 209 |