| Accession | TIGR02527 |
| Name | dot_icm_IcmQ |
| Function | Dot/Icm secretion system protein IcmQ |
| Gene Symbol | icmQ |
| Trusted Cutoff | 99.10 |
| Domain Trusted Cutoff | 99.10 |
| Noise Cutoff | 98.85 |
| Domain Noise Cutoff | 98.85 |
| Isology Type | equivalog |
| HMM Length | 179 |
| Author | Haft DH |
| Entry Date | Mar 15 2005 1:14PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Members of this protein family are the IcmQ component of Dot/Icm secretion systems, as found in obligate intracellular pathogens Legionella pneumophila and Coxiella burnetii. While this system resembles type IV secretion systems and has been called a form of type IV, the literature now seems to favor calling this the Dot/Icm system. This protein was shown to be essential for translocation (PMID:15661013). |
| References | RM 15661013
RT The Legionella IcmS-IcmW protein complex is important for Dot/Icm-mediated protein translocation.
RA Ninio S, Zuckman-Cholon DM, Cambronne ED, Roy CR.
RL Mol Microbiol. 2005 Feb;55(3):912-26. |
