Accession | TIGR02394 |
Name | rpoS_proteo |
Function | RNA polymerase sigma factor RpoS |
Gene Symbol | rpoS |
Trusted Cutoff | 378.70 |
Domain Trusted Cutoff | 378.70 |
Noise Cutoff | 339.75 |
Domain Noise Cutoff | 339.75 |
Isology Type | equivalog |
HMM Length | 285 |
Mainrole Category | Cellular processes |
Subrole Category | Adaptations to atypical conditions |
Gene Ontology Term | GO:0006352: transcription initiation, DNA-dependent biological_process |
| GO:0006950: response to stress biological_process |
| GO:0016987: sigma factor activity molecular_function |
Author | Haft DH |
Entry Date | Dec 7 2004 10:59AM |
Last Modified | Feb 14 2011 3:27PM |
Comment | A sigma factor is a DNA-binding protein protein that binds to the DNA-directed RNA polymerase core to produce the holoenzyme capable of initiating transcription at specific sites. Different sigma factors act in vegetative growth, heat shock, extracytoplasmic functions (ECF), etc. This model represents the clade of sigma factors called RpoS (also called sigma-38, KatF, etc.), found only in Proteobacteria. This sigma factor is induced in stationary phase (in response to the stress of nutrient limitation) and becomes the second prinicipal sigma factor at that time. RpoS is a member of the larger Sigma-70 subfamily (TIGR02937) and most closely related to RpoD (TIGR02393). |
References | RM 8475100
RT Heterogeneity of the principal sigma factor in Escherichia coli: the rpoS gene product, sigma 38, is a second principal sigma factor of RNA polymerase in stationary-phase Escherichia coli.
RA Tanaka K, Takayanagi Y, Fujita N, Ishihama A, Takahashi H.
RL Proc Natl Acad Sci U S A. 1993 Apr 15;90(8):3511-5. |