| Accession | TIGR02358 |
| Name | thia_cytX |
| Function | putative hydroxymethylpyrimidine transporter CytX |
| Gene Symbol | cytX |
| Trusted Cutoff | 309.85 |
| Domain Trusted Cutoff | 309.85 |
| Noise Cutoff | 170.55 |
| Domain Noise Cutoff | 170.55 |
| Isology Type | hypoth_equivalog |
| HMM Length | 386 |
| Mainrole Category | Transport and binding proteins |
| Subrole Category | Nucleosides, purines and pyrimidines |
| Author | Haft DH |
| Entry Date | Oct 19 2004 3:08PM |
| Last Modified | May 25 2011 6:51PM |
| Comment | On the basis of a phylogenomic study of thiamine biosythetic, salvage, and transporter genes and a highly conserved RNA element THI, this protein family has been identified as a probable transporter of hydroxymethylpyrimidine (HMP), the phosphorylated (by ThiD) form of which gets joined (by ThiE) to hydroxyethylthiazole phosphate to make thiamine phosphate. |
| References | RM 12376536
RT Comparative genomics of thiamin biosynthesis in procaryotes. New genes and regulatory mechanisms.
RA Rodionov DA, Vitreschak AG, Mironov AA, Gelfand MS.
RL J Biol Chem. 2002 Dec 13;277(50):48949-59. |
