| Accession | TIGR02224 |
| Name | recomb_XerC |
| Function | tyrosine recombinase XerC |
| Gene Symbol | xerC |
| Trusted Cutoff | 335.15 |
| Domain Trusted Cutoff | 335.15 |
| Noise Cutoff | 316.75 |
| Domain Noise Cutoff | 316.75 |
| Isology Type | equivalog |
| HMM Length | 295 |
| Mainrole Category | DNA metabolism |
| Subrole Category | DNA replication, recombination, and repair |
| Gene Ontology Term | GO:0006310: DNA recombination biological_process |
| | GO:0009009: site-specific recombinase activity molecular_function |
| Author | Haft DH |
| Entry Date | Jun 16 2004 1:18PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | The phage integrase family describes a number of recombinases with tyrosine active sites that transiently bind covalently to DNA. Many are associated with mobile DNA elements, including phage, transposons, and phase variation loci. This model represents XerC, one of two closely related chromosomal proteins along with XerD (TIGR02225). XerC and XerD are site-specific recombinases which help resolve chromosome dimers to monomers for cell division after DNA replication. In species with a large chromosome and homologs of XerC on other replicons, the chomosomal copy was preferred for building this model. This model does not detect all XerC, as some apparent XerC examples score in the gray zone between trusted (450) and noise (410) cutoffs, along with some XerD examples. XerC and XerD interact with cell division protein FtsK. |
| References | DR PFAM; PF00589; Phage integrase family
DR PFAM; PF02899; Phage integrase, N-terminal SAM-like domain
RM 12823825
RT Species specificity in the activation of Xer recombination at dif by FtsK.
RA Yates J, Aroyo M, Sherratt DJ, Barre FX.
RL Mol Microbiol. 2003 Jul;49(1):241-9.
DR HAMAP; MF_01808; 124 of 155 |
