Accession | TIGR02108 |
Name | PQQ_syn_pqqB |
Function | coenzyme PQQ biosynthesis protein B |
Gene Symbol | pqqB |
Trusted Cutoff | 303.55 |
Domain Trusted Cutoff | 303.55 |
Noise Cutoff | 76.85 |
Domain Noise Cutoff | 76.85 |
Isology Type | equivalog |
HMM Length | 302 |
Mainrole Category | Biosynthesis of cofactors, prosthetic groups, and carriers |
Subrole Category | Other |
Gene Ontology Term | GO:0018189: pyrroloquinoline quinone biosynthetic process biological_process |
Author | Haft DH |
Entry Date | Jan 22 2004 1:03PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | This HMM describes coenzyme PQQ biosynthesis protein B, a gene required for the biosynthesis of pyrrolo-quinoline-quinone (coenzyme PQQ). PQQ is required for some glucose dehydrogenases and alcohol dehydrogenases. Note that this gene appears to be required for PQQ in biosynthesis in Methylobacterium extorquens (under the name pqqG) and in Klebiella pneumoniae but that the equivalent pqqV in Acinetobacter calcoaceticus is not necessary for heterologous expression of PQQ biosynthesis in E. coli. Based on this latter finding, it is suggested (Goosen, et al. 1989) that PqqB might be a transporter or a PQQ-dependent enzyme rather than a PQQ biosynthesis enzyme. |
References | RM 2536663
RT Acinetobacter calcoaceticus genes involved in biosynthesis of the coenzyme pyrrolo-quinoline-quinone: nucleotide sequence and expression in Escherichia coli K-12.
RA Goosen N, Horsman HP, Huinen RG, van de Putte P.
RL J Bacteriol. 1989 Jan; 171(1): 447-55.
DR HAMAP; MF_00653; 39 of 39 |
Genome Property | GenProp0170: coenzyme PQQ biosynthesis (HMM) |